[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"currency-rates":3,"$fyk2oeqxpb7bd":8,"compound-J-22279-2":171,"verified-suppliers-J-22279-2":295},{"rates":4,"source":7},{"USD":5,"CNY":6},1,6.689327,"live",{"rows":9,"total":170,"current":5,"size":145},[10,33,45,60,74,85,96,113,123,135,146,158],{"slug":11,"cid":12,"imgSvg":13,"name":14,"nameZh":15,"cas":16,"formula":17,"iupac":14,"category":18,"categoryName":19,"categoryEnName":20,"industry":21,"tags":22,"offersCount":24,"supplierCount":25,"bestOffer":26},"843627791009189888","J-1971488-8","\u002Fimages\u002Fchem_structures_svg\u002F399\u002F65845-61-6.svg","N-Methylcyclohexanamine hydrochloride","N-甲基环己胺盐酸盐","65845-61-6","C7H16ClN","acids","有机酸","Organic Acids","",[23],"In Stock",4,2,{"unitPrice":27,"pack":28,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},2.64,"500g","CNY","China","CN","in-stock",{"slug":34,"cid":35,"imgSvg":36,"name":37,"nameZh":38,"cas":39,"formula":40,"iupac":37,"category":18,"categoryName":19,"categoryEnName":20,"industry":21,"tags":41,"offersCount":24,"supplierCount":5,"bestOffer":42},"785882541994283008","J-1323843-4","\u002Fimages\u002Fchem_structures_svg\u002F104\u002F67627-18-3.svg","Potassium indigotrisulfonate","靛蓝三磺酸钾","67627-18-3","C16H7K3N2O11S3",[23],{"unitPrice":43,"pack":44,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},180,"5g",{"slug":46,"cid":47,"imgSvg":48,"name":49,"nameZh":50,"cas":51,"formula":52,"iupac":49,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":56,"offersCount":57,"supplierCount":25,"bestOffer":58},"785889752443260928","J-28559-9","\u002Fimages\u002Fchem_structures_svg\u002F292\u002F15060-55-6.svg","Ammonium tetrathiomolybdate","四硫钼酸铵","15060-55-6","H8MoN2S4","inorganic","无机化合物","Inorganic Chemicals",[23],7,{"unitPrice":59,"pack":28,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},24,{"slug":61,"cid":62,"imgSvg":63,"name":64,"nameZh":65,"cas":66,"formula":67,"iupac":64,"category":18,"categoryName":19,"categoryEnName":20,"industry":21,"tags":68,"offersCount":69,"supplierCount":25,"bestOffer":70},"855452191530422272","J-1994428-7","\u002Fimages\u002Fchem_structures_svg\u002F500\u002F16350-96-2.svg","N-benzylcyclohexanamine.hydrochloride","N-苄基环己胺盐酸盐","16350-96-2","C13H20ClN",[23],5,{"unitPrice":71,"pack":72,"currency":29,"origin":73,"originFlag":31,"moq":21,"stock":32},6,"1000g","中国",{"slug":75,"cid":76,"imgSvg":77,"name":78,"nameZh":79,"cas":80,"formula":81,"iupac":78,"category":18,"categoryName":19,"categoryEnName":20,"industry":21,"tags":82,"offersCount":25,"supplierCount":25,"bestOffer":83},"785871840001134592","J-982001-0","\u002Fimages\u002Fchem_structures_svg\u002F001\u002F10517-44-9.svg","1,3-Diaminopropane dihydrochloride","1,3-二氨基丙烷二盐酸盐","10517-44-9","C3H12Cl2N2",[23],{"unitPrice":84,"pack":28,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},3.78,{"slug":86,"cid":87,"imgSvg":88,"name":89,"nameZh":90,"cas":91,"formula":92,"iupac":89,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":93,"offersCount":57,"supplierCount":94,"bestOffer":95},"785880365658017792","J-14975-6","\u002Fimages\u002Fchem_structures_svg\u002F262\u002F12003-67-7.svg","Lithium aluminate","氧化铝锂","12003-67-7","AlHLiO2",[23],3,{"unitPrice":94,"pack":28,"currency":29,"origin":73,"originFlag":31,"moq":21,"stock":32},{"slug":97,"cid":98,"imgSvg":99,"name":100,"nameZh":101,"cas":102,"formula":103,"iupac":100,"category":104,"categoryName":105,"categoryEnName":106,"industry":21,"tags":107,"offersCount":108,"supplierCount":108,"bestOffer":109},"785871830249377792","J-6931-9","\u002Fimages\u002Fchem_structures_svg\u002F456\u002F58068-80-7.svg","1-Octanoylbenzotriazole","N-辛酰苯并三唑","58068-80-7","C14H19N3O","aromatics","芳香烃","Aromatic Hydrocarbons",[],0,{"unitPrice":110,"pack":21,"currency":111,"origin":21,"originFlag":21,"moq":21,"stock":112},9007199254740991,"USD","made-to-order",{"slug":114,"cid":115,"imgSvg":116,"name":117,"nameZh":118,"cas":119,"formula":120,"iupac":117,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":121,"offersCount":69,"supplierCount":25,"bestOffer":122},"785871842446413824","J-1960944-3","\u002Fimages\u002Fchem_structures_svg\u002F495\u002F10534-86-8.svg","Hexaamminecobalt(III) nitrate","六氨合钴(III)硝酸盐","10534-86-8","CoH18N9O9",[23],{"unitPrice":71,"pack":28,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},{"slug":124,"cid":125,"imgSvg":126,"name":127,"nameZh":128,"cas":129,"formula":130,"iupac":127,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":131,"offersCount":24,"supplierCount":25,"bestOffer":132},"785871842576437248","J-814544-6","\u002Fimages\u002Fchem_structures_svg\u002F221\u002F12037-42-2.svg","vanadium oxide","氧化钒","12037-42-2","O13V6",[23],{"unitPrice":133,"pack":134,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},112.8,"100g",{"slug":136,"cid":137,"imgSvg":138,"name":139,"nameZh":140,"cas":141,"formula":142,"iupac":139,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":143,"offersCount":57,"supplierCount":5,"bestOffer":144},"785871842647740416","J-1333345-2","\u002Fimages\u002Fchem_structures_svg\u002F479\u002F26490-63-1.svg","COBALT TETRAFLUOROBORATE HEXAHYDRATE","四氟化硼钴水合物","26490-63-1","B2CoF8H12O6",[23],{"unitPrice":145,"pack":134,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},12,{"slug":147,"cid":148,"imgSvg":149,"name":150,"nameZh":151,"cas":152,"formula":153,"iupac":150,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":154,"offersCount":155,"supplierCount":94,"bestOffer":156},"785871842698072064","J-814953-0","\u002Fimages\u002Fchem_structures_svg\u002F432\u002F72259-10-0.svg","Copper(II) tetrafluoroborate hexahydrate","六水合四氟硼酸铜(II)","72259-10-0","B2CuF8H12O6",[23],10,{"unitPrice":157,"pack":28,"currency":29,"origin":21,"originFlag":21,"moq":21,"stock":32},2.6,{"slug":159,"cid":160,"imgSvg":161,"name":162,"nameZh":163,"cas":164,"formula":165,"iupac":162,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":166,"offersCount":25,"supplierCount":5,"bestOffer":168},"785871863254355968","J-1990080-7","\u002Fimages\u002Fchem_structures_svg\u002F149\u002F123333-60-8.svg","Cerium(IV) sulfate hydrate","铈(IV)硫酸盐水合物","123333-60-8","CeH2O9S2",[167],"Made to Order",{"unitPrice":169,"pack":28,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},5.6,3204,{"slug":172,"cid":173,"imgSvg":174,"name":175,"nameZh":175,"cas":176,"formula":177,"iupac":175,"mdl":21,"mw":178,"category":179,"categoryName":180,"categoryEnName":181,"industry":21,"tags":182,"synonyms":183,"properties":189,"ghs":209,"offers":210,"activity":211,"upstream":227,"downstream":228,"customs":229,"safetyRows":242,"toxicity":253,"updatedAt":254,"isProhibited":255,"related":256,"__ts":293,"__lang":294,"__slug":173},"785882198346567680","J-22279-2","\u002Fimages\u002Fchem_structures_svg\u002F198\u002F4303-67-7.svg","1-十二烷基咪唑","4303-67-7","C15H28N2","236.39600","pharma","医药中间体","Pharma Intermediates",[],[184,185,186,187,188],"N-十二烷基咪唑","1-十二咪唑","N-正十二烷基咪唑","1-十二烷基-1H-咪唑","十二烷基咪唑",[190,194,198,201,205],{"label":191,"labelZh":192,"value":193},"Exact Mass","精确质量","236.22500",{"label":195,"labelZh":196,"value":197},"PSA","其他信息","17.82000",{"label":199,"labelZh":199,"value":200},"LogP","4.80400",{"label":202,"labelZh":203,"value":204},"Storage Conditions","储存条件","2~8℃，Seal",{"label":206,"labelZh":207,"value":208},"Computational Chemistry","计算化学","1.疏水参数计算参考值（XlogP）:5.5\n2.氢键供体数量:0\n3.氢键受体数量:1\n4.可旋转化学键数量:11\n5.互变异构体数量:无\n6.拓扑分子极性表面积:17.8\n7.重原子数量:17\n8.表面电荷:0\n9.复杂度:159\n10.同位素原子数量:0\n11.确定原子立构中心数量:0\n12.不确定原子立构中心数量:0\n13.确定化学键立构中心数量:0\n14.不确定化学键立构中心数量:0\n15.共价键单元数量:1",null,[],[212,215,218,221,224],{"key":213,"value":214},"描述","1-Dodecylimidazole (N-Dodecylimidazole) 是一种溶酶体活性洗涤剂和细胞毒性剂。1-Dodecylimidazole 通过其在溶酶体中的酸依赖性积累、溶酶体膜的破坏和半胱氨酸蛋白酶释放到细胞质中而导致细胞死亡。1-Dodecylimidazole 具有降胆固醇和广谱抗真菌活性。",{"key":216,"value":217},"相关类别","研究领域\n>>\n癌症\n信号通路\n>>\n抗感染\n>>\n真菌",{"key":219,"value":220},"体外研究","十二烷基咪唑是一种酸性洗涤剂,pKa为6.3,对培养细胞具有细胞毒性。十二烷基咪唑对EMT-6和MGH-U1细胞具有细胞外pH依赖性细胞毒作用。细胞杀伤是剂量依赖性的,在PHE6.0比PHE7.0高100倍[4]。",{"key":222,"value":223},"体内研究","1-十二烷基咪唑的降胆固醇活性部分源于2,3-氧化角鲨烯甾醇环化酶对胆固醇生物合成的抑制[2]。1-十二烷基咪唑(150 mg\u002Fkg体重；胃管法；每天10天)的血清胆固醇浓度低于对照组大鼠[2]。动物模型：雄性大鼠[2]剂量：150mg\u002Fkg体重给药：胃管给药；每日10天结果：血清胆固醇浓度明显低于未经治疗的动物。",{"key":225,"value":226},"参考文献","[1].\nWilson PD, et al. A relationship between multidrug resistance and growth-state dependent cytotoxicity of the lysosomotropic detergent N-dodecylimidazole. Biochem Biophys Res Commun. 1991;176(3):1377-1382.\n[2].\nAtkin SD, et al. The isolation of 2,3-oxidosqualene from the liver of rats treated with 1-dodecylimidazole, a novel hypocholesterolaemic agent. Biochem J. 1972;130(1):153-157.\n[3].\nFirestone RA, et al. Lysosomotropic agents. 7. Broad-spectrum antifungal activity of lysosomotropic detergents. J Med Chem. 1987;30(8):1519-1521.\n[4].\nBoyer MJ, et al. pH dependent cytotoxicity of N-dodecylimidazole: a compound that acquires detergent properties under acidic conditions. Br J Cancer. 1993;67(1):81-87.",[],[],[230,233,236,239],{"key":231,"value":232},"海关编码","2933290090",{"key":234,"value":235},"中文概述","2933290090. 其他结构含非稠合咪唑环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%",{"key":237,"value":238},"申报要素","品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期",{"key":240,"value":241},"Summary","2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%",[243,246,249,252],{"key":244,"value":245},"危害码 (欧洲)","Xi",{"key":247,"value":248},"风险声明 (欧洲)","36\u002F37\u002F38",{"key":250,"value":251},"安全声明 (欧洲)","37\u002F39-26",{"key":231,"value":232},"\u003Ctd>\n\n\u003Cp>\u003Ca href=\"\u002Fen\u002Fcas\u002F4303-67-7_364017.html#duXinDiv\">1-十二烷基咪唑毒性英文版\u003C\u002Fa>\u003C\u002Fp>\n\n\u003C\u002Ftd>","2026-08-21T07:51:12.859463Z",false,[257,263,269,275,281,287],{"slug":258,"cid":259,"name":260,"nameZh":261,"cas":262},"854297947846742016","J-1135609-5","Carbamic acid, N-[(3S)-3-piperidinyl]-, 1,1-dimethylethyl ester, hydrochloride (1:1)","N-[(3S)-哌啶-3-基]氨基甲酸叔丁酯盐酸盐","1416450-55-9",{"slug":264,"cid":265,"name":266,"nameZh":267,"cas":268},"785898090472148992","J-1119003-5","2-(1-piperazinyl)pyrimidine dihydrochloride","2-嘧啶基哌嗪二盐酸盐","94021-22-4",{"slug":270,"cid":271,"name":272,"nameZh":273,"cas":274},"855020115098341376","J-1994365-7","(3-bromo-5-Methylpyridin-2-yl)Methanamine hydrochloride","(3-溴-5-甲基吡啶-2-基)甲胺盐酸盐","1257535-62-8",{"slug":276,"cid":277,"name":278,"nameZh":279,"cas":280},"785896374758543360","J-1051994-9","5-Bromo-2,3-dihydro-1H-indole hydrochloride","5-溴-2,3-二氢-1H-吲哚盐酸盐","15861-32-2",{"slug":282,"cid":283,"name":284,"nameZh":285,"cas":286},"785892490338111488","J-1074200-4","3-Methyl-2-benzothiazolinone hydrazone hydrochloride monohydrate","3-甲基-2-苯并噻唑啉酮腙盐酸盐一水合物","38894-11-0",{"slug":288,"cid":289,"name":290,"nameZh":291,"cas":292},"785880531895062528","J-16061-4","2,2':6',2''-Terpyridine","2,2':6',2''-三联吡啶","1148-79-4",1792682243423,"zh-CN",[]]