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Order",{"unitPrice":169,"pack":28,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},5.6,3204,{"slug":172,"cid":173,"imgSvg":174,"name":175,"nameZh":175,"cas":176,"formula":177,"iupac":175,"mdl":21,"mw":178,"category":179,"categoryName":180,"categoryEnName":181,"industry":21,"tags":182,"synonyms":183,"properties":187,"ghs":246,"offers":260,"activity":261,"upstream":289,"downstream":314,"customs":322,"safetyRows":323,"toxicity":356,"msds":357,"updatedAt":358,"isProhibited":359,"related":360,"__ts":397,"__lang":398,"__slug":173},"785881589161660416","J-20198-0","\u002Fimages\u002Fchem_structures_svg\u002F150\u002F362-07-2.svg","2-甲氧基雌二醇","362-07-2","C19H26O3","302.408","alcohols","醇类","Alcohols",[],[184,185,186],"2-甲氧雌二醇","2-甲氧基-β-雌二醇","3,17β-二羟基-2-甲氧基-1,3,5(10)-雌甾三烯",[188,193,198,203,208,212,216,219,223,227,231,235,239,243],{"label":189,"labelZh":190,"value":191,"prop":192},"Melting Point","熔点","188-190°C","meltingPoint",{"label":194,"labelZh":195,"value":196,"prop":197},"Boiling Point","沸点","464.4±45.0 °C at 760 mmHg","boilingPoint",{"label":199,"labelZh":200,"value":201,"prop":202},"Density","密度","1.2±0.1 g\u002Fcm3","density",{"label":204,"labelZh":205,"value":206,"prop":207},"Flash Point","闪点","234.7±28.7 °C","flashPoint",{"label":209,"labelZh":210,"value":211},"Exact Mass","精确质量","302.188202",{"label":213,"labelZh":214,"value":215},"PSA","其他信息","49.69000",{"label":217,"labelZh":217,"value":218},"LogP","3.84",{"label":220,"labelZh":221,"value":222},"Appearance","外观性状","灰白色固体",{"label":224,"labelZh":225,"value":226},"Vapor Pressure","蒸汽压","0.0±1.2 mmHg at 25°C",{"label":228,"labelZh":229,"value":230},"Refractive Index","折射率","1.586",{"label":232,"labelZh":233,"value":234},"Storage Conditions","储存条件","-20°储存。",{"label":236,"labelZh":237,"value":238},"Additional Property","水溶解性","DMSO: 10 mg\u002FmL",{"label":240,"labelZh":241,"value":242},"Molecular Structure","分子结构","1、 摩尔折射率：86.18\n2、 摩尔体积（m\n3\n\u002Fmol）：256.6\n3、 等张比容（90.2K）：672.0\n4、 表面张力（dyne\u002Fcm）：47.0\n5、 极化率（10\n-24\ncm\n3\n）：34.16",{"label":236,"labelZh":244,"value":245},"更多","一、物性数据\n性状：淡黄色结晶\n密度（g\u002FmL,25\u002F4℃）：不可用\n相对蒸汽密度（g\u002FmL,空气=1）：不可用\n熔点（ºC）：188-190\n沸点（ºC,常压）：不可用\n沸点（ºC,5.2kPa）：不可用\n折射率：不可用\n闪点（ºC）：不可用\n比旋光度（º）：不可用\n自燃点或引燃温度（ºC）：不可用\n蒸气压（kPa,25ºC）：不可用\n饱和蒸气压（kPa,60ºC）：不可用\n燃烧热（KJ\u002Fmol）：不可用\n临界温度（ºC）：不可用\n临界压力（KPa）：不可用\n油水（辛醇\u002F水）分配系数的对数值：不可用\n爆炸上限（%,V\u002FV）：不可用\n爆炸下限（%,V\u002FV）：不可用\n溶解性：溶于N,N-二甲基亚砜",{"pictogram":247,"signal":248,"hazards":249},"Acute Toxicity \u002F Health Hazard \u002F Environmental Hazard","Danger",[250,251,252,253,254,255,256,257,258,259],"H301 — Toxic if swallowed \u002F 吞咽会中毒","H311 — Toxic in contact with skin \u002F 皮肤接触会中毒","H331 — Toxic if inhaled \u002F 吸入会中毒","H315 — Causes skin irritation \u002F 造成皮肤刺激","H319 — Causes serious eye irritation \u002F 造成严重眼刺激","H335 — May cause respiratory irritation \u002F 可能造成呼吸道刺激","H350 — May cause cancer \u002F 可能致癌","H360 — May damage fertility or the unborn child \u002F 可能对生育能力或胎儿造成伤害","H372 — Causes damage to organs through prolonged exposure \u002F 长期或反复接触会对器官造成损害","H410 — Very toxic to aquatic life with long lasting effects \u002F 对水生生物毒性极大并具有长期持续影响",[],[262,265,268,271,274,277,280,283,286],{"key":263,"value":264},"描述","2-Methoxyestradiol是血管生成抑制剂和凋亡诱导剂,具有有效的抗肿瘤活性。 2-Methoxyestradiol也可破坏微管的稳定。",{"key":266,"value":267},"相关类别","信号通路\n>>\n细胞凋亡\n>>\n细胞凋亡\n信号通路\n>>\n细胞周期\u002FDNA损伤\n>>\n微管\u002F微管蛋白\n信号通路\n>>\n细胞骨架\n>>\n微管\u002F微管蛋白\n研究领域\n>>\n癌症\n天然产物\n>>\n类固醇",{"key":269,"value":270},"靶点","Human Endogenous Metabolite",{"key":272,"value":273},"体外研究","2-甲氧基雌二醇(5-100μM)以浓度依赖性方式抑制纯化微管蛋白的装配,在200μM2-甲氧基雌二醇(2ME2)下具有最大抑制(60％)。然而,对于含有微管相关蛋白的微管,解聚微管需要显着更高的2-甲氧基雌二醇浓度,并且在500μM2-甲氧基雌二醇时聚合物质量仅减少13％。 4μM2-甲氧基雌二醇使平均生长速率降低17％,动态性降低27％。对于有丝分裂停滞的IC50的活间期MCF7细胞(1.2μM),2-甲氧基雌二醇显着抑制平均微管生长速率,持续时间和长度,以及整体动态性,与其体外作用一致,并且没有任何可观察到的微管解聚。 2-甲氧基雌二醇在许多活跃分裂的细胞类型中诱导G2-M阻滞和凋亡,同时保留静止细胞。 2-甲氧基雌二醇在秋水仙碱位点处或附近与微管蛋白结合,抑制微管组装,并且已显示高浓度解聚细胞中的微管。 2-甲氧基雌二醇诱导G2-M阻滞和细胞凋亡,许多活跃分裂也阻断有丝分裂并抑制内皮细胞迁移[1]。 2-甲氧基雌二醇(2-ME)降低缺氧条件下培养的HIF-1α和HIF-2α核染色。当细胞在常氧和缺氧条件下暴露于2-甲氧基雌二醇时,HIF-1α和HIF-2αmRNA水平显着降低。 2-甲氧基雌二醇是一种抗血管生成,抗增殖和促凋亡剂,可抑制HIF-1α蛋白水平及其转录活性。在96小时时,与DMSO处理的细胞(分别为66.2±7.2和101.2±2.3％; p = 0.04)相比,在10μM2-甲氧基雌二醇处理的A549细胞中发现生长速率的显着降低。浓度为10μM的2-甲氧基雌二醇用于凋亡和HIF-1α和HIF-2α表达测定,这是由于当细胞在常氧条件下在72小时温育时发现该浓度的显着性。与较低O2浓度的细胞(5.8±0.2％; p = 0.003)相比,在常氧条件下用10μM2-甲氧基雌二醇处理的细胞中观察到细胞凋亡的显着增加[2]。",{"key":275,"value":276},"体内研究","为了研究2ME2对葡萄膜炎发展的影响,将C57BL\u002F6小鼠随机分成两组并用IRBP肽免疫。 2ME2组从第0天至第13天腹膜内开始2-甲氧基雌二醇(15mg\u002Fkg),而对照组给予载体。 2-甲氧基雌二醇(2ME2)组的病变评分为0.30±0.30,显着低于对照组2.09±0.28(p \u003C0.05),每组含5只小鼠[3]。用2-甲氧基雌二醇(60-600mg\u002Fkg\u002Fd)治疗导致肿瘤生长的剂量依赖性抑制。在2-甲氧基雌二醇处理组中,具有强烈的哌莫胺阳性染色(+++)的细胞百分比显着降低(60mg\u002Fkg\u002Fd为36.0％,200和600mg\u002Fkg\u002Fd为0％)与媒介物治疗组(86.5％)。这可能是由于2-甲氧基雌二醇治疗后剂量依赖性地显着抑制肿瘤生长[4]。",{"key":278,"value":279},"激酶实验","将微管蛋白（2.75 mg \u002F mL）装配成稳态[在100 mM PIPES中含有1 mM EGTA和1 mM MgSO4（PEM100）和1 mM GTP，35°C 45分钟]，含有2-甲氧基雌二醇（最终药物浓度） 1-500μM）。将最终的DMSO和乙醇浓度分别调节至1％和5％。 2-甲氧基雌二醇≤5μM的浓度对微管聚合物质量没有影响，因此大多数实验使用20-500μM的2-甲氧基雌二醇。用2-甲氧基雌二醇孵育30分钟，此时微管解聚最大，微管在35℃离心30分钟，从沉淀中除去上清液。将微管颗粒在0.2M NaOH中溶解过夜，测定上清液和颗粒的蛋白质浓度[1]。",{"key":281,"value":282},"细胞实验","用绿色荧光蛋白（GFP）-α-微管蛋白稳定转染的MCF7乳腺癌细胞在补充有非必需氨基酸，0.1％青霉素\u002F链霉素，10％胎牛血清和0.4mg \u002F mL G418的DMEM中于37℃培养。 5％的二氧化碳。用GFP-α-微管蛋白进行MCF7细胞的转染。为了评估有丝分裂指数，将细胞以6×104 \u002F 2mL的浓度接种到六孔板中。 48小时后，将细胞在不存在或存在2-甲氧基雌二醇的情况下以100nM至30μM的浓度温育20小时。为了收集漂浮和附着的细胞，收集培养基;用Versene（137mM NaCl，2.7mM KCl，1.5mM KH 2 PO 4,8.1mM Na 2 HPO 4和0.5mM EDTA）冲洗附着的细胞，通过胰蛋白酶消化分离，并加回到培养基中。通过离心收集细胞并用10％福尔马林固定30分钟，在冰冷的甲醇中透化10分钟，并用4'，6-二脒基-2-苯基吲哚染色以显现细胞核。结果是七个实验的平均值和SE，每个实验对每个浓度计数500个细胞。有丝分裂IC50是诱导最大有丝分裂积累一半的药物浓度[1]。",{"key":284,"value":285},"动物实验","使用小鼠[3] 6~8周龄的C57BL \u002F 6小鼠。 C57BL \u002F 6小鼠在尾部皮下免疫0.1mL，在大腿部位用IRBP抗原复合物皮下免疫0.05mL。同时注射500ng百日咳毒素。这一天定为第0天。然后将小鼠分成4组，每组包含5只小鼠。在0-13天，0-6天和7-13天腹腔注射15mg \u002F kg 2-甲氧基雌二醇或载体。在第14天，在安乐死后收集眼睛或淋巴结。用ip注射载体（60,200或600mg \u002F kg \u002F天的2-甲氧基雌二醇\u002F Panzem）处理大鼠[4] Fischer 344大鼠（平均体重= 150g，每组n = 6）。在最初的肿瘤细胞注射后第8天开始连续9天。每组使用三只大鼠第二次重复实验。",{"key":287,"value":288},"参考文献","[1].\nKamath K, et al. 2-Methoxyestradiol suppresses microtubule dynamics and arrests mitosis without depolymerizing microtubules. Mol Cancer Ther. 2006 Sep;5(9):2225-33.\n[2].\nAquino-Gálvez A, et al. Effects of 2-methoxyestradiol on apoptosis and HIF-1α and HIF-2α expression in lung cancer cells under normoxia and hypoxia. Oncol Rep. 2016 Jan;35(1):577-83.\n[3].\nXu L, et al. 2-Methoxyestradiol Alleviates Experimental Autoimmune Uveitis by Inhibiting Lymphocytes Proliferation and T Cell Differentiation. Biomed Res Int. 2016;2016:7948345.\n[4].\nKang SH, et al. Antitumor effect of 2-methoxyestradiol in a rat orthotopic brain tumor model. Cancer Res. 2006, 66(24),11991-11997.",[290,296,302,308],{"slug":291,"cid":292,"name":293,"nameZh":293,"cas":294,"imgSvg":295},"785872255388225500","J-1969590-9","2-甲氧基雌素酮","362-08-3","https:\u002F\u002Fapi.chemical.xiaokangmed.com\u002Fimages\u002Fchem_structures_svg\u002F112\u002F362-08-3.svg",{"slug":297,"cid":298,"name":299,"nameZh":299,"cas":300,"imgSvg":301},"785883707385843700","J-8864-6","甲醇钠","124-41-4","https:\u002F\u002Fapi.chemical.xiaokangmed.com\u002Fimages\u002Fchem_structures_svg\u002F254\u002F124-41-4.svg",{"slug":303,"cid":304,"name":305,"nameZh":305,"cas":306,"imgSvg":307},"785881916749385700","J-1117167-4","2-溴雌二醇","15833-07-5","https:\u002F\u002Fapi.chemical.xiaokangmed.com\u002Fimages\u002Fchem_structures_svg\u002F460\u002F15833-07-5.svg",{"slug":309,"cid":310,"name":311,"nameZh":311,"cas":312,"imgSvg":313},"785891925243727900","J-31545-8","雌二醇","50-28-2","https:\u002F\u002Fapi.chemical.xiaokangmed.com\u002Fimages\u002Fchem_structures_svg\u002F341\u002F50-28-2.svg",[315,321],{"slug":316,"cid":317,"name":318,"nameZh":318,"cas":319,"imgSvg":320},"785884066179190800","J-22780-9","2-羟基-17β-雌二醇","362-05-0","https:\u002F\u002Fapi.chemical.xiaokangmed.com\u002Fimages\u002Fchem_structures_svg\u002F226\u002F362-05-0.svg",{"slug":291,"cid":292,"name":293,"nameZh":293,"cas":294,"imgSvg":295},[],[324,327,329,332,335,338,341,344,347,350,353],{"key":325,"value":326},"符号","GHS06, GHS08, GHS09",{"key":328,"value":248},"信号词",{"key":330,"value":331},"危害声明","H301 + H311 + H331-H315-H319-H335-H350-H360-H372-H410",{"key":333,"value":334},"警示性声明","P201-P261-P273-P280-P301 + P310-P305 + P351 + P338",{"key":336,"value":337},"个人防护装备","Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges",{"key":339,"value":340},"危害码 (欧洲)","T: Toxic;",{"key":342,"value":343},"风险声明 (欧洲)","R23\u002F24\u002F25",{"key":345,"value":346},"安全声明 (欧洲)","S22-S26-S36\u002F37\u002F39-S45-S53",{"key":348,"value":349},"危险品运输编码","UN 3077 9\u002FPG 3",{"key":351,"value":352},"WGK德国","3",{"key":354,"value":355},"RTECS号","KG7537500","\u003Ctd>\n\n\u003Cp>\u003Cstrong>2-甲氧基雌二醇毒理学数据:\u003C\u002Fstrong>\u003C\u002Fp>\n\u003Cp>\u003C\u002Fp>\u003Cp>二、毒理学数据：  \u003C\u002Fp>\n\u003Cp>急性毒性：不可用。 \u003C\u002Fp>\n\u003Cp>\u003C\u002Fp>\n\u003Cp>\u003Cstrong>2-甲氧基雌二醇生态学数据:\u003C\u002Fstrong>\u003C\u002Fp>\n\u003Cp>\u003C\u002Fp>\u003Cp>三、生态学数据：  \u003C\u002Fp>\n\u003Cp>1、其它有害作用：该物质对环境可能有危害，对水体应给予特别注意。 \u003C\u002Fp>\n\u003Cp>\u003C\u002Fp>\n\u003Cp>\u003Ca href=\"\u002Fen\u002Fcas\u002F362-07-2_332863.html#duXinDiv\">2-甲氧基雌二醇毒性英文版\u003C\u002Fa>\u003C\u002Fp>\n\n\u003C\u002Ftd>","\u003Ctd>\n\n\u003Cb>2-甲氧基-β-雌二醇\u003C\u002Fb>\n\u003Cb>修改号码：5.3\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块1. 化学品\u003C\u002Fstrong>\n\u003Cbr \u002F> 产品名称：\n\u003Cb>2-Methoxy-β-estradiol\u003C\u002Fb>\n\u003Cbr \u002F> 修改号码：\n\u003Cb>5.3\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块2. 危险性概述\u003C\u002Fstrong>\n\u003Cbr \u002F>\n\u003Cb>GHS分类\u003C\u002Fb>\n\u003Cbr \u002F> 　物理性危害未分类\n\u003Cbr \u002F> 　健康危害\n\u003Cbr \u002F> 致癌性\n\u003Cb>第2级\u003C\u002Fb>\n\u003Cbr \u002F> 　环境危害未分类\n\u003Cbr \u002F>\n\u003Cb>GHS标签元素\u003C\u002Fb>\n\u003Cbr \u002F> 　图标或危害标志\n\u003Cbr \u002F> 　信号词警告\n\u003Cbr \u002F> 　危险描述怀疑会致癌\n\u003Cbr \u002F> 　防范说明\n\u003Cbr \u002F>\n\u003Cb>[预防]\u003C\u002Fb>使用前获取特定手册。\n\u003Cbr \u002F> 处理前必须阅读并理解所有安全措施。\n\u003Cbr \u002F> 使用个人所需的防护用具。\n\u003Cbr \u002F>\n\u003Cb>[急救措施]\u003C\u002Fb>\n\u003Cb>如接触到或相关接触：求医\u002F就诊。\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>[储存]\u003C\u002Fb>存放处须加锁。\n\u003Cbr \u002F>\n\u003Cb>[废弃处置]\u003C\u002Fb>\n\u003Cb>根据当地政府规定把物品\u002F容器交与工业废弃处理机构。\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块3. 成分\u002F组成信息\u003C\u002Fstrong>\n\u003Cbr \u002F>\n\u003Cb>单一物质\u002F混和物\u003C\u002Fb>单一物质\n\u003Cbr \u002F>\n\u003Cb>化学名(中文名)：\u003C\u002Fb>\n\u003Cb>2-甲氧基-β-雌二醇\u003C\u002Fb>\n\u003Cbr \u002F> 百分比：\n\u003Cb>>97.0%(GC)\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>CAS编码：\u003C\u002Fb>\n\u003Cb>362-07-2\u003C\u002Fb>\n\u003Cbr \u002F> 分子式：\n\u003Cb>C19H26O3\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块4. 急救措施\u003C\u002Fstrong>\n\u003Cbr \u002F> 吸入：\n\u003Cb>将受害者移到新鲜空气处，保持呼吸通畅，休息。求医\u002F就诊。\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>2-甲氧基-β-雌二醇\u003C\u002Fb>\n\u003Cb>修改号码：5.3\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块4. 急救措施\u003C\u002Fstrong>\n\u003Cbr \u002F> 皮肤接触：\n\u003Cb>立即去除\u002F脱掉所有被污染的衣物。用大量肥皂和水轻轻洗。\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>求医\u002F就诊。\u003C\u002Fb>\n\u003Cbr \u002F> 眼睛接触：用水小心清洗几分钟。如果方便，易操作，摘除隐形眼镜。\n\u003Cbr \u002F>\n\u003Cb>求医\u002F就诊。\u003C\u002Fb>\n\u003Cbr \u002F> 食入：\n\u003Cb>求医\u002F就诊。漱口。\u003C\u002Fb>\n\u003Cbr \u002F> 紧急救助者的防护：救援者需要穿戴个人防护用品，比如橡胶手套和气密性护目镜。\n\u003Cbr \u002F>\n\n\u003Cstrong>模块5. 消防措施\u003C\u002Fstrong>\n\u003Cbr \u002F> 合适的灭火剂：干粉，泡沫，雾状水，二氧化碳\n\u003Cbr \u002F> 特定方法：从上风处灭火，根据周围环境选择合适的灭火方法。\n\u003Cbr \u002F> 非相关人员应该撤离至安全地方。\n\u003Cbr \u002F> 周围一旦着火：如果安全，移去可移动容器。\n\u003Cbr \u002F> 消防员的特殊防护用具：灭火时，一定要穿戴个人防护用品。\n\u003Cbr \u002F>\n\n\u003Cstrong>模块6. 泄漏应急处理\u003C\u002Fstrong>\n\u003Cbr \u002F> 个人防护措施，防护用具，\n\u003Cb>使用特殊的个人防护用品（针对有毒颗粒的P3过滤式空气呼吸器）。远离溢出物\u002F泄露\u003C\u002Fb>\n\u003Cbr \u002F> 紧急措施：处并处在上风处。\n\u003Cbr \u002F> 泄露区应该用安全带等圈起来，控制非相关人员进入。\n\u003Cbr \u002F> 环保措施：防止进入下水道。\n\u003Cbr \u002F> 控制和清洗的方法和材料：清扫收集粉尘，封入密闭容器。注意切勿分散。附着物或收集物应该立即根据合适的\n\u003Cbr \u002F> 法律法规处置。\n\u003Cbr \u002F>\n\n\u003Cstrong>模块7. 操作处置与储存\u003C\u002Fstrong>\n\u003Cbr \u002F> 处理\n\u003Cbr \u002F> 技术措施：在通风良好处进行处理。穿戴合适的防护用具。防止粉尘扩散。处理后彻底清洗双手\n\u003Cbr \u002F> 和脸。\n\u003Cbr \u002F> 注意事项：如果可能，使用封闭系统。如果粉尘或浮质产生，使用局部排气。\n\u003Cbr \u002F> 操作处置注意事项：避免所有部位的接触！\n\u003Cbr \u002F> 贮存\n\u003Cbr \u002F> 储存条件：保持容器密闭。存放于凉爽、阴暗处。\n\u003Cbr \u002F> 存放处须加锁。\n\u003Cbr \u002F> 远离不相容的材料比如氧化剂存放。\n\u003Cbr \u002F> 包装材料：依据法律。\n\u003Cbr \u002F>\n\n\u003Cstrong>模块8. 接触控制和个体防护\u003C\u002Fstrong>\n\u003Cbr \u002F> 工程控制：尽可能安装封闭体系或局部排风系统。同时安装淋浴器和洗眼器。\n\u003Cbr \u002F> 个人防护用品\n\u003Cbr \u002F> 　呼吸系统防护：\n\u003Cb>防尘面具，自携式呼吸器（SCBA），供气呼吸器等。使用通过政府标准的呼吸器。依\u003C\u002Fb>\n\u003Cbr \u002F> 据当地和政府法规。\n\u003Cbr \u002F> 　手部防护：防渗手套。\n\u003Cbr \u002F> 　眼睛防护：护目镜。如果情况需要，佩戴面具。\n\u003Cbr \u002F> 　皮肤和身体防护：防渗防护服。如果情况需要，穿戴防护靴。\n\u003Cbr \u002F>\n\n\u003Cstrong>模块9. 理化特性\u003C\u002Fstrong>\n\u003Cbr \u002F> 固体\n\u003Cbr \u002F>\n\u003Cb>外形（20°C）：\u003C\u002Fb>\n\u003Cbr \u002F> 外观：\n\u003Cb>晶体-粉末\u003C\u002Fb>\n\u003Cbr \u002F> 颜色：\n\u003Cb>白色-微浅黄色\u003C\u002Fb>\n\u003Cbr \u002F> 气味：无资料\n\u003Cbr \u002F>\n\u003Cb>pH:\u003C\u002Fb>无数据资料\n\u003Cbr \u002F>\n\u003Cb>2-甲氧基-β-雌二醇\u003C\u002Fb>\n\u003Cb>修改号码：5.3\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块9. 理化特性\u003C\u002Fstrong>\n\u003Cbr \u002F> 熔点：\n\u003Cb>187°C\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>沸点\u002F沸程\u003C\u002Fb>无资料\n\u003Cbr \u002F> 闪点：无资料\n\u003Cbr \u002F> 爆炸特性\n\u003Cbr \u002F> 　爆炸下限：无资料\n\u003Cbr \u002F> 　爆炸上限：无资料\n\u003Cbr \u002F> 密度：无资料\n\u003Cbr \u002F> 溶解度：\n\u003Cbr \u002F>\n\u003Cb>[水]\u003C\u002Fb>无资料\n\u003Cbr \u002F>\n\u003Cb>[其他溶剂]\u003C\u002Fb>\n\u003Cbr \u002F> 极微溶于：四氢呋喃\n\u003Cbr \u002F>\n\u003Cb>log水分配系数 =\u003C\u002Fb>\n\u003Cb>2.87\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块10. 稳定性和反应性\u003C\u002Fstrong>\n\u003Cbr \u002F> 化学稳定性：一般情况下稳定。\n\u003Cbr \u002F> 危险反应的可能性：未报道特殊反应性。\n\u003Cbr \u002F> 须避免接触的物质氧化剂\n\u003Cbr \u002F>\n\u003Cb>危险的分解产物:\u003C\u002Fb>\n\u003Cb>一氧化碳, 二氧化碳\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块11. 毒理学信息\u003C\u002Fstrong>\n\u003Cbr \u002F> 急性毒性：无资料\n\u003Cbr \u002F> 对皮肤腐蚀或刺激：无资料\n\u003Cbr \u002F> 对眼睛严重损害或刺激：无资料\n\u003Cbr \u002F> 生殖细胞变异原性：\n\u003Cb>mmo-smc 31.6 umol\u002FL\u002F6H\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>msc-ham-emb 100 ug\u002FL\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>cyt-ham-emb 0.3 mg\u002FL\u002F24H\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>mnt-hmn-oth 10 umol\u002FL\u002F3H\u003C\u002Fb>\n\u003Cbr \u002F> 致癌性：\n\u003Cbr \u002F>\n\u003Cb>IARC =\u003C\u002Fb>无资料\n\u003Cbr \u002F>\n\u003Cb>NTP =\u003C\u002Fb>无资料\n\u003Cbr \u002F> 生殖毒性：无资料\n\u003Cbr \u002F>\n\u003Cb>RTECS 号码:\u003C\u002Fb>\n\u003Cb>KG7537500\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块12. 生态学信息\u003C\u002Fstrong>\n\u003Cbr \u002F> 生态毒性：\n\u003Cbr \u002F> 鱼类：无资料\n\u003Cbr \u002F> 甲壳类：无资料\n\u003Cbr \u002F> 藻类：无资料\n\u003Cbr \u002F>\n\u003Cb>残留性 \u002F 降解性：\u003C\u002Fb>无资料\n\u003Cbr \u002F>\n\u003Cb>潜在生物累积 （BCF):\u003C\u002Fb>无资料\n\u003Cbr \u002F> 土壤中移动性\n\u003Cbr \u002F>\n\u003Cb>　log水分配系数：\u003C\u002Fb>\n\u003Cb>2.87\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>　土壤吸收系数 （Koc）：\u003C\u002Fb>无资料\n\u003Cbr \u002F> 　亨利定律无资料\n\u003Cbr \u002F>\n\u003Cb>constant(PaM3\u002Fmol):\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块13. 废弃处置\u003C\u002Fstrong>\n\u003Cbr \u002F> 如果可能，回收处理。请咨询当地管理部门。建议在可燃溶剂中溶解混合，在装有后燃和洗涤装置的化学焚烧炉中\n\u003Cbr \u002F> 焚烧。废弃处置时请遵守国家、地区和当地的所有法规。\n\u003Cbr \u002F>\n\u003Cb>2-甲氧基-β-雌二醇\u003C\u002Fb>\n\u003Cb>修改号码：5.3\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块14. 运输信息\u003C\u002Fstrong>\n\u003Cbr \u002F> 联合国分类：与联合国分类标准不一致\n\u003Cbr \u002F>\n\u003Cb>UN编号：\u003C\u002Fb>未列明\n\u003Cbr \u002F>\n\n\u003Cstrong>模块15. 法规信息\u003C\u002Fstrong>\n\u003Cbr \u002F>\n\u003Cb>《危险化学品安全管理条例》（2002年1月26日国务院发布，2011年2月16日修订）: 针对危险化学品的安全使用、\u003C\u002Fb>\n\u003Cbr \u002F> 生产、储存、运输、装卸等方面均作了相应的规定。\n\u003Cbr \u002F>\n\u003Cbr \u002F>\n\n\u003Cstrong> 模块16 - 其他信息 \u003C\u002Fstrong>\n\u003Cbr \u002F>N\u002FA\n\u003Cbr \u002F>\u003Cbr \u002F>\u003Cbr \u002F>\u003Cbr \u002F>\u003Cbr \u002F>\n\u003Cbr \u002F>\n\u003C\u002Ftd>","2026-08-21T07:51:12.859463Z",false,[361,367,373,379,385,391],{"slug":362,"cid":363,"name":364,"nameZh":365,"cas":366},"785893589807796224","J-1336183-5","Lead(II) methanethiolate","甲硫醇铅","35029-96-0",{"slug":368,"cid":369,"name":370,"nameZh":371,"cas":372},"785883130081841152","J-7166-0","1H,1H-Undecafluoro-1-hexanol","1H,1H-十一氟-1-己醇","423-46-1",{"slug":374,"cid":375,"name":376,"nameZh":377,"cas":378},"785897951850401792","J-48487-1","D-erythro-Sphingosine","D-鞘氨醇","123-78-4",{"slug":380,"cid":381,"name":382,"nameZh":383,"cas":384},"785892627638652928","J-33176-0","2,6-Dichloroindophenol sodium salt","2,6-二氯靛酚钠","620-45-1",{"slug":386,"cid":387,"name":388,"nameZh":389,"cas":390},"785897136192491520","J-1519177-1","2-Perfluoropropoxy-2,3,3,3-tetrafluoropropanol","2-全氟丙氧基-2,3,3,3-四氟丙醇","26537-88-2",{"slug":392,"cid":393,"name":394,"nameZh":395,"cas":396},"785897617765699584","J-47482-5","Estriol","雌三醇","50-27-1",1792670974865,"zh-CN",[]]