[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"currency-rates":3,"$fyk2oeqxpb7bd":8,"compound-J-1985182-4":171,"verified-suppliers-J-1985182-4":316},{"rates":4,"source":7},{"USD":5,"CNY":6},1,6.691314,"live",{"rows":9,"total":170,"current":5,"size":145},[10,33,45,60,74,85,96,113,123,135,146,158],{"slug":11,"cid":12,"imgSvg":13,"name":14,"nameZh":15,"cas":16,"formula":17,"iupac":14,"category":18,"categoryName":19,"categoryEnName":20,"industry":21,"tags":22,"offersCount":24,"supplierCount":25,"bestOffer":26},"843627791009189888","J-1971488-8","\u002Fimages\u002Fchem_structures_svg\u002F399\u002F65845-61-6.svg","N-Methylcyclohexanamine hydrochloride","N-甲基环己胺盐酸盐","65845-61-6","C7H16ClN","acids","有机酸","Organic Acids","",[23],"In Stock",4,2,{"unitPrice":27,"pack":28,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},2.64,"500g","CNY","China","CN","in-stock",{"slug":34,"cid":35,"imgSvg":36,"name":37,"nameZh":38,"cas":39,"formula":40,"iupac":37,"category":18,"categoryName":19,"categoryEnName":20,"industry":21,"tags":41,"offersCount":24,"supplierCount":5,"bestOffer":42},"785882541994283008","J-1323843-4","\u002Fimages\u002Fchem_structures_svg\u002F104\u002F67627-18-3.svg","Potassium indigotrisulfonate","靛蓝三磺酸钾","67627-18-3","C16H7K3N2O11S3",[23],{"unitPrice":43,"pack":44,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},180,"5g",{"slug":46,"cid":47,"imgSvg":48,"name":49,"nameZh":50,"cas":51,"formula":52,"iupac":49,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":56,"offersCount":57,"supplierCount":25,"bestOffer":58},"785889752443260928","J-28559-9","\u002Fimages\u002Fchem_structures_svg\u002F292\u002F15060-55-6.svg","Ammonium tetrathiomolybdate","四硫钼酸铵","15060-55-6","H8MoN2S4","inorganic","无机化合物","Inorganic Chemicals",[23],7,{"unitPrice":59,"pack":28,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},24,{"slug":61,"cid":62,"imgSvg":63,"name":64,"nameZh":65,"cas":66,"formula":67,"iupac":64,"category":18,"categoryName":19,"categoryEnName":20,"industry":21,"tags":68,"offersCount":69,"supplierCount":25,"bestOffer":70},"855452191530422272","J-1994428-7","\u002Fimages\u002Fchem_structures_svg\u002F500\u002F16350-96-2.svg","N-benzylcyclohexanamine.hydrochloride","N-苄基环己胺盐酸盐","16350-96-2","C13H20ClN",[23],5,{"unitPrice":71,"pack":72,"currency":29,"origin":73,"originFlag":31,"moq":21,"stock":32},6,"1000g","中国",{"slug":75,"cid":76,"imgSvg":77,"name":78,"nameZh":79,"cas":80,"formula":81,"iupac":78,"category":18,"categoryName":19,"categoryEnName":20,"industry":21,"tags":82,"offersCount":25,"supplierCount":25,"bestOffer":83},"785871840001134592","J-982001-0","\u002Fimages\u002Fchem_structures_svg\u002F001\u002F10517-44-9.svg","1,3-Diaminopropane dihydrochloride","1,3-二氨基丙烷二盐酸盐","10517-44-9","C3H12Cl2N2",[23],{"unitPrice":84,"pack":28,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},3.78,{"slug":86,"cid":87,"imgSvg":88,"name":89,"nameZh":90,"cas":91,"formula":92,"iupac":89,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":93,"offersCount":57,"supplierCount":94,"bestOffer":95},"785880365658017792","J-14975-6","\u002Fimages\u002Fchem_structures_svg\u002F262\u002F12003-67-7.svg","Lithium aluminate","氧化铝锂","12003-67-7","AlHLiO2",[23],3,{"unitPrice":94,"pack":28,"currency":29,"origin":73,"originFlag":31,"moq":21,"stock":32},{"slug":97,"cid":98,"imgSvg":99,"name":100,"nameZh":101,"cas":102,"formula":103,"iupac":100,"category":104,"categoryName":105,"categoryEnName":106,"industry":21,"tags":107,"offersCount":108,"supplierCount":108,"bestOffer":109},"785871830249377792","J-6931-9","\u002Fimages\u002Fchem_structures_svg\u002F456\u002F58068-80-7.svg","1-Octanoylbenzotriazole","N-辛酰苯并三唑","58068-80-7","C14H19N3O","aromatics","芳香烃","Aromatic Hydrocarbons",[],0,{"unitPrice":110,"pack":21,"currency":111,"origin":21,"originFlag":21,"moq":21,"stock":112},9007199254740991,"USD","made-to-order",{"slug":114,"cid":115,"imgSvg":116,"name":117,"nameZh":118,"cas":119,"formula":120,"iupac":117,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":121,"offersCount":69,"supplierCount":25,"bestOffer":122},"785871842446413824","J-1960944-3","\u002Fimages\u002Fchem_structures_svg\u002F495\u002F10534-86-8.svg","Hexaamminecobalt(III) nitrate","六氨合钴(III)硝酸盐","10534-86-8","CoH18N9O9",[23],{"unitPrice":71,"pack":28,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},{"slug":124,"cid":125,"imgSvg":126,"name":127,"nameZh":128,"cas":129,"formula":130,"iupac":127,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":131,"offersCount":24,"supplierCount":25,"bestOffer":132},"785871842576437248","J-814544-6","\u002Fimages\u002Fchem_structures_svg\u002F221\u002F12037-42-2.svg","vanadium oxide","氧化钒","12037-42-2","O13V6",[23],{"unitPrice":133,"pack":134,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},112.8,"100g",{"slug":136,"cid":137,"imgSvg":138,"name":139,"nameZh":140,"cas":141,"formula":142,"iupac":139,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":143,"offersCount":57,"supplierCount":5,"bestOffer":144},"785871842647740416","J-1333345-2","\u002Fimages\u002Fchem_structures_svg\u002F479\u002F26490-63-1.svg","COBALT TETRAFLUOROBORATE HEXAHYDRATE","四氟化硼钴水合物","26490-63-1","B2CoF8H12O6",[23],{"unitPrice":145,"pack":134,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},12,{"slug":147,"cid":148,"imgSvg":149,"name":150,"nameZh":151,"cas":152,"formula":153,"iupac":150,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":154,"offersCount":155,"supplierCount":94,"bestOffer":156},"785871842698072064","J-814953-0","\u002Fimages\u002Fchem_structures_svg\u002F432\u002F72259-10-0.svg","Copper(II) tetrafluoroborate hexahydrate","六水合四氟硼酸铜(II)","72259-10-0","B2CuF8H12O6",[23],10,{"unitPrice":157,"pack":28,"currency":29,"origin":21,"originFlag":21,"moq":21,"stock":32},2.6,{"slug":159,"cid":160,"imgSvg":161,"name":162,"nameZh":163,"cas":164,"formula":165,"iupac":162,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":166,"offersCount":25,"supplierCount":5,"bestOffer":168},"785871863254355968","J-1990080-7","\u002Fimages\u002Fchem_structures_svg\u002F149\u002F123333-60-8.svg","Cerium(IV) sulfate hydrate","铈(IV)硫酸盐水合物","123333-60-8","CeH2O9S2",[167],"Made to Order",{"unitPrice":169,"pack":28,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},5.6,3204,{"slug":172,"cid":173,"imgSvg":174,"name":175,"nameZh":175,"cas":176,"formula":177,"iupac":175,"mdl":21,"mw":178,"category":179,"categoryName":180,"categoryEnName":181,"industry":21,"tags":182,"synonyms":183,"properties":188,"ghs":232,"offers":233,"activity":234,"upstream":250,"downstream":269,"customs":275,"safetyRows":276,"updatedAt":277,"isProhibited":278,"related":279,"__ts":314,"__lang":315,"__slug":173},"785896935457296384","J-1985182-4","\u002Fimages\u002Fchem_structures_svg\u002F465\u002F99200-09-6.svg","奈必洛尔","99200-09-6","C22H25F2NO4","405.43500","organic","有机化合物","Organic Compounds",[],[184,185,186,187],"奈比洛尔","双[2-(6-氟苯并二氢吡喃-2-基)-2-羟基乙基]胺","莱必伍罗","奈必洛尔(混旋)",[189,194,199,204,209,213,217,220,224,228],{"label":190,"labelZh":191,"value":192,"prop":193},"Melting Point","熔点","155-156°C(lit.)","meltingPoint",{"label":195,"labelZh":196,"value":197,"prop":198},"Boiling Point","沸点","600.5ºC at 760 mmHg","boilingPoint",{"label":200,"labelZh":201,"value":202,"prop":203},"Density","密度","1.309 g\u002Fcm3","density",{"label":205,"labelZh":206,"value":207,"prop":208},"Flash Point","闪点","316.9ºC","flashPoint",{"label":210,"labelZh":211,"value":212},"Exact Mass","精确质量","405.17500",{"label":214,"labelZh":215,"value":216},"PSA","其他信息","70.95000",{"label":218,"labelZh":218,"value":219},"LogP","2.75450",{"label":221,"labelZh":222,"value":223},"Appearance","外观性状","气味",{"label":225,"labelZh":226,"value":227},"Refractive Index","折射率","1.58",{"label":229,"labelZh":230,"value":231},"Storage Conditions","储存条件","20°C",null,[],[235,238,241,244,247],{"key":236,"value":237},"描述","(Rac)-奈比洛尔((Rac)-R 065824)是奈比洛利的外消旋异构体。奈比洛尔是一种选择性β1肾上腺素能受体拮抗剂,IC50值为0.8 nM。奈比洛尔可以在乙醇诱导的心脏毒性早期阻止Nox2\u002FNADPH氧化酶的上调和脂质过氧化。血管舒张活性[1][2]。",{"key":239,"value":240},"相关类别","研究领域\n>>\n心血管疾病\n信号通路\n>>\nG 蛋白偶联受体\u002FG 蛋白\n>>\n肾上腺素能受体",{"key":242,"value":243},"靶点","IC50: 0.8 nM (β1-adrenergic receptor)[1]",{"key":245,"value":246},"体内研究","奈比洛尔(10 mg\u002Fkg；每天7天)显著改善内皮功能障碍并增加P-VASP水平；防止NOS III解耦；显著抑制血管紧张素II治疗大鼠的NADPH氧化酶[3]。",{"key":248,"value":249},"参考文献","[1].\ndo Vale GT, et al. Nebivolol Prevents Up-Regulation of Nox2\u002FNADPH Oxidase and Lipoperoxidation in the Early Stages of Ethanol-Induced Cardiac Toxicity. Cardiovasc Toxicol. 2021 Mar;21(3):224-235.\n[2].\nCockcroft JR, et al. Nebivolol vasodilates human forearm vasculature: evidence for an L-arginine\u002FNO-dependent mechanism. J Pharmacol Exp Ther. 1995 Sep;274(3):1067-71.\n[3].\nOelze M, et al. Nebivolol inhibits superoxide formation by NADPH oxidase and endothelial dysfunction in angiotensin II-treated rats. Hypertension. 2006 Oct;48(4):677-84.",[251,257,263],{"slug":252,"cid":253,"name":254,"nameZh":254,"cas":255,"imgSvg":256},"785894445445812200","J-1502944-5","6-氟-2-(环氧乙烷-2H)...","99199-90-3","https:\u002F\u002Fapi.chemical.xiaokangmed.com\u002Fimages\u002Fchem_structures_svg\u002F289\u002F99199-90-3.svg",{"slug":258,"cid":259,"name":260,"nameZh":260,"cas":261,"imgSvg":262},"785875980156670000","J-11571-5","二苄胺","103-49-1","https:\u002F\u002Fapi.chemical.xiaokangmed.com\u002Fimages\u002Fchem_structures_svg\u002F222\u002F103-49-1.svg",{"slug":264,"cid":265,"name":266,"nameZh":266,"cas":267,"imgSvg":268},"785882960883617800","J-6315-5","苄胺","100-46-9","https:\u002F\u002Fapi.chemical.xiaokangmed.com\u002Fimages\u002Fchem_structures_svg\u002F394\u002F100-46-9.svg",[270],{"slug":271,"cid":272,"name":184,"nameZh":184,"cas":273,"imgSvg":274},"785894235889995800","J-1501536-1","9920-09-6","https:\u002F\u002Fapi.chemical.xiaokangmed.com\u002Fimages\u002Fchem_structures_svg\u002F181\u002F9920-09-6.svg",[],[],"2026-08-21T07:51:12.859463Z",false,[280,286,291,297,303,308],{"slug":281,"cid":282,"name":283,"nameZh":284,"cas":285},"785872510607429632","J-1334045-0","calcium saccharin","糖精钙","6485-34-3",{"slug":287,"cid":288,"name":289,"nameZh":289,"cas":290},"785914490636996608","J-1241469-7","2-Chloro-4-(1-dibenzofuranyl)-6-(1-naphthalenyl)-1,3,5-triazine","2417986-80-0",{"slug":292,"cid":293,"name":294,"nameZh":295,"cas":296},"785871874079854592","J-1110697-5","Crystal Violet","结晶紫","548-62-9",{"slug":298,"cid":299,"name":300,"nameZh":301,"cas":302},"785895040399446016","J-1110640-3","Solvent Red 27","溶剂红27","1320-06-5",{"slug":304,"cid":305,"name":306,"nameZh":306,"cas":307},"785911446427930624","J-69315-4","9-Bromo-10-(naphthalen-1-yl-d7)anthracene-1,2,3,4,5,6,7,8-d8","2330770-73-3",{"slug":309,"cid":310,"name":311,"nameZh":312,"cas":313},"785897866148188160","J-1065587-2","Noscapine","那可丁","128-62-1",1792644987688,"zh-CN",[]]