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iv)预处理弱地减弱了8-羟基-2-(二正丙氨基)四氢萘的抑制作用。相反,剂量低至0.1mg\u002Fkg iv的WAY-100635完全阻断了8-羟基-2-(二正丙氨基)四氢萘的作用。 WAY-100635在5-HT1A自身受体上的拮抗作用与其增加神经元活性的能力密切相关。总体而言,WAY-100635似乎充当选择性5-HT1A拮抗剂,而(S)-WAY-100135则不起作用。用WAY-100635获得的结果证实了我们先前用螺哌隆获得的结果,并进一步支持了5-HT1A自身受体介导的反馈抑制在生理条件下起作用的假设[2]。",{"key":224,"value":225},"参考文献","[1].\nForster EA, et al. 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