[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"currency-rates":3,"$fyk2oeqxpb7bd":8,"compound-J-1955875-0":171,"verified-suppliers-J-1955875-0":322},{"rates":4,"source":7},{"USD":5,"CNY":6},1,6.691314,"live",{"rows":9,"total":170,"current":5,"size":145},[10,33,45,60,74,85,96,113,123,135,146,158],{"slug":11,"cid":12,"imgSvg":13,"name":14,"nameZh":15,"cas":16,"formula":17,"iupac":14,"category":18,"categoryName":19,"categoryEnName":20,"industry":21,"tags":22,"offersCount":24,"supplierCount":25,"bestOffer":26},"843627791009189888","J-1971488-8","\u002Fimages\u002Fchem_structures_svg\u002F399\u002F65845-61-6.svg","N-Methylcyclohexanamine hydrochloride","N-甲基环己胺盐酸盐","65845-61-6","C7H16ClN","acids","有机酸","Organic Acids","",[23],"In Stock",4,2,{"unitPrice":27,"pack":28,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},2.64,"500g","CNY","China","CN","in-stock",{"slug":34,"cid":35,"imgSvg":36,"name":37,"nameZh":38,"cas":39,"formula":40,"iupac":37,"category":18,"categoryName":19,"categoryEnName":20,"industry":21,"tags":41,"offersCount":24,"supplierCount":5,"bestOffer":42},"785882541994283008","J-1323843-4","\u002Fimages\u002Fchem_structures_svg\u002F104\u002F67627-18-3.svg","Potassium indigotrisulfonate","靛蓝三磺酸钾","67627-18-3","C16H7K3N2O11S3",[23],{"unitPrice":43,"pack":44,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},180,"5g",{"slug":46,"cid":47,"imgSvg":48,"name":49,"nameZh":50,"cas":51,"formula":52,"iupac":49,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":56,"offersCount":57,"supplierCount":25,"bestOffer":58},"785889752443260928","J-28559-9","\u002Fimages\u002Fchem_structures_svg\u002F292\u002F15060-55-6.svg","Ammonium tetrathiomolybdate","四硫钼酸铵","15060-55-6","H8MoN2S4","inorganic","无机化合物","Inorganic Chemicals",[23],7,{"unitPrice":59,"pack":28,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},24,{"slug":61,"cid":62,"imgSvg":63,"name":64,"nameZh":65,"cas":66,"formula":67,"iupac":64,"category":18,"categoryName":19,"categoryEnName":20,"industry":21,"tags":68,"offersCount":69,"supplierCount":25,"bestOffer":70},"855452191530422272","J-1994428-7","\u002Fimages\u002Fchem_structures_svg\u002F500\u002F16350-96-2.svg","N-benzylcyclohexanamine.hydrochloride","N-苄基环己胺盐酸盐","16350-96-2","C13H20ClN",[23],5,{"unitPrice":71,"pack":72,"currency":29,"origin":73,"originFlag":31,"moq":21,"stock":32},6,"1000g","中国",{"slug":75,"cid":76,"imgSvg":77,"name":78,"nameZh":79,"cas":80,"formula":81,"iupac":78,"category":18,"categoryName":19,"categoryEnName":20,"industry":21,"tags":82,"offersCount":25,"supplierCount":25,"bestOffer":83},"785871840001134592","J-982001-0","\u002Fimages\u002Fchem_structures_svg\u002F001\u002F10517-44-9.svg","1,3-Diaminopropane dihydrochloride","1,3-二氨基丙烷二盐酸盐","10517-44-9","C3H12Cl2N2",[23],{"unitPrice":84,"pack":28,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},3.78,{"slug":86,"cid":87,"imgSvg":88,"name":89,"nameZh":90,"cas":91,"formula":92,"iupac":89,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":93,"offersCount":57,"supplierCount":94,"bestOffer":95},"785880365658017792","J-14975-6","\u002Fimages\u002Fchem_structures_svg\u002F262\u002F12003-67-7.svg","Lithium aluminate","氧化铝锂","12003-67-7","AlHLiO2",[23],3,{"unitPrice":94,"pack":28,"currency":29,"origin":73,"originFlag":31,"moq":21,"stock":32},{"slug":97,"cid":98,"imgSvg":99,"name":100,"nameZh":101,"cas":102,"formula":103,"iupac":100,"category":104,"categoryName":105,"categoryEnName":106,"industry":21,"tags":107,"offersCount":108,"supplierCount":108,"bestOffer":109},"785871830249377792","J-6931-9","\u002Fimages\u002Fchem_structures_svg\u002F456\u002F58068-80-7.svg","1-Octanoylbenzotriazole","N-辛酰苯并三唑","58068-80-7","C14H19N3O","aromatics","芳香烃","Aromatic Hydrocarbons",[],0,{"unitPrice":110,"pack":21,"currency":111,"origin":21,"originFlag":21,"moq":21,"stock":112},9007199254740991,"USD","made-to-order",{"slug":114,"cid":115,"imgSvg":116,"name":117,"nameZh":118,"cas":119,"formula":120,"iupac":117,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":121,"offersCount":69,"supplierCount":25,"bestOffer":122},"785871842446413824","J-1960944-3","\u002Fimages\u002Fchem_structures_svg\u002F495\u002F10534-86-8.svg","Hexaamminecobalt(III) nitrate","六氨合钴(III)硝酸盐","10534-86-8","CoH18N9O9",[23],{"unitPrice":71,"pack":28,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},{"slug":124,"cid":125,"imgSvg":126,"name":127,"nameZh":128,"cas":129,"formula":130,"iupac":127,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":131,"offersCount":24,"supplierCount":25,"bestOffer":132},"785871842576437248","J-814544-6","\u002Fimages\u002Fchem_structures_svg\u002F221\u002F12037-42-2.svg","vanadium oxide","氧化钒","12037-42-2","O13V6",[23],{"unitPrice":133,"pack":134,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},112.8,"100g",{"slug":136,"cid":137,"imgSvg":138,"name":139,"nameZh":140,"cas":141,"formula":142,"iupac":139,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":143,"offersCount":57,"supplierCount":5,"bestOffer":144},"785871842647740416","J-1333345-2","\u002Fimages\u002Fchem_structures_svg\u002F479\u002F26490-63-1.svg","COBALT TETRAFLUOROBORATE HEXAHYDRATE","四氟化硼钴水合物","26490-63-1","B2CoF8H12O6",[23],{"unitPrice":145,"pack":134,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},12,{"slug":147,"cid":148,"imgSvg":149,"name":150,"nameZh":151,"cas":152,"formula":153,"iupac":150,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":154,"offersCount":155,"supplierCount":94,"bestOffer":156},"785871842698072064","J-814953-0","\u002Fimages\u002Fchem_structures_svg\u002F432\u002F72259-10-0.svg","Copper(II) tetrafluoroborate hexahydrate","六水合四氟硼酸铜(II)","72259-10-0","B2CuF8H12O6",[23],10,{"unitPrice":157,"pack":28,"currency":29,"origin":21,"originFlag":21,"moq":21,"stock":32},2.6,{"slug":159,"cid":160,"imgSvg":161,"name":162,"nameZh":163,"cas":164,"formula":165,"iupac":162,"category":53,"categoryName":54,"categoryEnName":55,"industry":21,"tags":166,"offersCount":25,"supplierCount":5,"bestOffer":168},"785871863254355968","J-1990080-7","\u002Fimages\u002Fchem_structures_svg\u002F149\u002F123333-60-8.svg","Cerium(IV) sulfate hydrate","铈(IV)硫酸盐水合物","123333-60-8","CeH2O9S2",[167],"Made to Order",{"unitPrice":169,"pack":28,"currency":29,"origin":30,"originFlag":31,"moq":21,"stock":32},5.6,3204,{"slug":172,"cid":173,"imgSvg":174,"name":175,"nameZh":175,"cas":176,"formula":177,"iupac":175,"mdl":21,"mw":178,"category":179,"categoryName":180,"categoryEnName":181,"industry":21,"tags":182,"synonyms":183,"properties":185,"ghs":212,"offers":213,"activity":214,"upstream":227,"downstream":252,"customs":265,"safetyRows":278,"toxicity":280,"updatedAt":281,"isProhibited":282,"related":283,"__ts":320,"__lang":321,"__slug":173},"785882532376743936","J-1955875-0","\u002Fimages\u002Fchem_structures_svg\u002F177\u002F533-45-9.svg","氯美噻唑","533-45-9","C6H8ClNS","198.11300","pharma","医药中间体","Pharma Intermediates",[],[184],"5-(2-氯乙基)-4-甲基噻唑",[186,190,194,198,202,205,208],{"label":187,"labelZh":187,"value":188,"prop":189},"Boiling Point","245.8ºC at 760 mmHg","boilingPoint",{"label":191,"labelZh":191,"value":192,"prop":193},"Density","1.218 g\u002Fcm3","density",{"label":195,"labelZh":195,"value":196,"prop":197},"Flash Point","102.4ºC","flashPoint",{"label":199,"labelZh":200,"value":201},"Exact Mass","精确质量","196.98300",{"label":203,"labelZh":203,"value":204},"PSA","41.13000",{"label":206,"labelZh":206,"value":207},"LogP","3.03480",{"label":209,"labelZh":210,"value":211},"Storage Conditions","储存条件","库房低温通风干燥",null,[],[215,218,221,224],{"key":216,"value":217},"描述","Chlormethiazole 是一种有效的口服 GABAA 激动剂。 Chlormethiazole 还可以抑制人肝微粒体中的细胞色素 P450 亚型: CYP2A6 和 CYP2E1。Chlormethiazole 有抗惊厥作用,具有治疗惊厥性癫痫的潜力。",{"key":219,"value":220},"相关类别","信号通路\n>>\n代谢酶\u002F蛋白酶\n>>\n细胞色素P450\n信号通路\n>>\n跨膜转运\n>>\nGABA受体\n研究领域\n>>\n神经疾病\n信号通路\n>>\n神经信号通路\n>>\nGABA受体",{"key":222,"value":223},"体外研究","在没有GABA的情况下,氯噻唑(1mm)对α1\u002Fβ1\u002Fγ2或α1\u002Fβ2\u002Fγ2亚基的细胞产生大的全细胞电流[1]。氯噻唑激活α1\u002Fβ1\u002Fγ2-和α1\u002Fβ2\u002Fγ2-细胞中的GABAA电流,EC50值分别为0.3和1.5mm[1]。低浓度的氯噻唑(30μm)也能增强GABA在两种细胞类型中的作用,相当于效力的3倍增加,最大电流增加到1.8倍(1)。氯噻唑抑制人肝微粒体中细胞色素P450亚型CYP2A6和CYP2E1的IC50值分别为24μM和42μM,同时所有其他亚型的IC50值均大于300μM[2]。",{"key":225,"value":226},"参考文献","[1].\nNelson RM, et al.Electrophysiological actions of gamma-aminobutyric acid and clomethiazole on recombinant GABA(A) receptors.Eur J Pharmacol. 2002 Oct 11;452(3):255-62.\n[2].\nStresser DM, et al. Selective Time- and NADPH-Dependent Inhibition of Human CYP2E1 by Clomethiazole.Drug Metab Dispos. 2016 Aug;44(8):1424-30",[228,234,240,246],{"slug":229,"cid":230,"name":231,"nameZh":231,"cas":232,"imgSvg":233},"785872240582332400","J-1991485-7","4-甲基-5-噻唑乙醇","137-00-8","https:\u002F\u002Fapi.chemical.xiaokangmed.com\u002Fimages\u002Fchem_structures_svg\u002F267\u002F137-00-8.svg",{"slug":235,"cid":236,"name":237,"nameZh":237,"cas":238,"imgSvg":239},"785880919478112300","J-1467730-8","5-(2-乙氧基乙基)-4-甲基噻唑","853261-35-5","https:\u002F\u002Fapi.chemical.xiaokangmed.com\u002Fimages\u002Fchem_structures_svg\u002F344\u002F853261-35-5.svg",{"slug":241,"cid":242,"name":243,"nameZh":243,"cas":244,"imgSvg":245},"785884408476340200","J-1306893-0","3-氯-4-氧-1-戊醇","13045-13-1","https:\u002F\u002Fapi.chemical.xiaokangmed.com\u002Fimages\u002Fchem_structures_svg\u002F224\u002F13045-13-1.svg",{"slug":247,"cid":248,"name":249,"nameZh":249,"cas":250,"imgSvg":251},"785882869263241200","J-1410151-3","3,5-二氯-2-戊酮","58371-98-5","https:\u002F\u002Fapi.chemical.xiaokangmed.com\u002Fimages\u002Fchem_structures_svg\u002F266\u002F58371-98-5.svg",[253,259],{"slug":254,"cid":255,"name":256,"nameZh":256,"cas":257,"imgSvg":258},"785894703466811400","J-38725-5","4-甲基-5-乙烯基噻唑","1759-28-0","https:\u002F\u002Fapi.chemical.xiaokangmed.com\u002Fimages\u002Fchem_structures_svg\u002F344\u002F1759-28-0.svg",{"slug":260,"cid":261,"name":262,"nameZh":262,"cas":263,"imgSvg":264},"785898298664816600","J-1526759-5","2-(4-甲基噻唑-5-基)乙胺","58981-35-4","https:\u002F\u002Fapi.chemical.xiaokangmed.com\u002Fimages\u002Fchem_structures_svg\u002F439\u002F58981-35-4.svg",[266,269,272,275],{"key":267,"value":268},"海关编码","2934100090",{"key":270,"value":271},"中文概述","2934100090. 结构上含有一个非稠合噻唑环的化合物(不论是否氢化). 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%",{"key":273,"value":274},"申报要素","品名, 成分含量, 用途",{"key":276,"value":277},"Summary","2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%",[279],{"key":267,"value":268},"\u003Ctd>\n\n\u003Cp>\u003Ca href=\"\u002Fen\u002Fcas\u002F533-45-9_405039.html#duXinDiv\">氯美噻唑毒性英文版\u003C\u002Fa>\u003C\u002Fp>\n\n\u003C\u002Ftd>","2026-08-21T07:51:12.859463Z",false,[284,290,296,302,308,314],{"slug":285,"cid":286,"name":287,"nameZh":288,"cas":289},"785898313726562304","J-1031608-9","1H-Imidazole-1-propanamine, dihydrochloride","3-(咪唑-1-基)-丙胺双盐酸盐","17583-33-4",{"slug":291,"cid":292,"name":293,"nameZh":294,"cas":295},"785881637186441216","J-1118091-1","2-CHLORO-5-(CHLOROMETHYL)PYRIDINE HYDROCHLORIDE","2-氯-5-氯甲基吡啶盐酸盐","82674-16-6",{"slug":297,"cid":298,"name":299,"nameZh":300,"cas":301},"853334401180766208","J-1118263-2","4-(Piperidin-4-yl)pyridine hydrochloride","4-(哌啶-4-基)吡啶盐酸盐","196191-99-8",{"slug":303,"cid":304,"name":305,"nameZh":306,"cas":307},"785939024182251520","J-624056-3","4-bromo-1-methyl-1H-pyrazole hydrochloride","4-溴-1-甲基-1H-吡唑盐酸盐","1881331-69-6",{"slug":309,"cid":310,"name":311,"nameZh":312,"cas":313},"785883443375378432","J-1455223-2","4-(Pyridin-4-yl)phenylboronic acid","(4-(吡啶-4-基)苯基)硼酸","1045332-30-6",{"slug":315,"cid":316,"name":317,"nameZh":318,"cas":319},"785884628983484416","J-1319482-8","Sodium 1H-indol-3-ylacetate","3-吲哚乙酸钠","6505-45-9",1792600849132,"zh-CN",[]]