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Incompatible with strong oxidizing agents.",{"label":240,"labelZh":241,"value":242},"Additional Property","水溶解性","\u003C0.1 g\u002F100 mL at 20 ºC",{"label":244,"labelZh":245,"value":246},"Molecular Structure","分子结构","五、分子性质数据：\n1、 摩尔折射率：73.50\n2、 摩尔体积（m\n3\n\u002Fmol）：233.5\n3、 等张比容（90.2K）：610.4\n4、 表面张力（dyne\u002Fcm）：46.7\n5、 极化率（10\n-24\ncm\n3\n）：29.14",{"label":248,"labelZh":249,"value":250},"Computational Chemistry","计算化学","1.疏水参数计算参考值（XlogP）:无\n2.氢键供体数量:1\n3.氢键受体数量:5\n4.可旋转化学键数量:7\n5.互变异构体数量:无\n6.拓扑分子极性表面积83.1\n7.重原子数量:19\n8.表面电荷:0\n9.复杂度:374\n10.同位素原子数量:0\n11.确定原子立构中心数量:0\n12.不确定原子立构中心数量:0\n13.确定化学键立构中心数量:0\n14.不确定化学键立构中心数量:0\n15.共价键单元数量:1",{"label":240,"labelZh":252,"value":253},"更多","1. 性状：白色结晶性粉末。\n2. 密度（g\u002FmL,25\u002F4℃）：未确定\n3. 相对蒸汽密度（g\u002FmL,空气=1）：未确定\n4. 熔点（ºC）：194-196\n5. 沸点（ºC,常压）：未确定\n6. 沸点（ºC,5.2kPa）：未确定\n7. 折射率：未确定\n8. 闪点（ºC）：未确定\n9. 比旋光度（º）：未确定\n10. 自燃点或引燃温度（ºC）：未确定\n11. 蒸气压（kPa,25ºC）：未确定\n12. 饱和蒸气压（kPa,60ºC）：未确定\n13. 燃烧热（KJ\u002Fmol）：未确定\n14. 临界温度（ºC）：未确定\n15. 临界压力（KPa）：未确定\n16. 油水（辛醇\u002F水）分配系数的对数值：未确定\n17. 爆炸上限（%,V\u002FV）：未确定\n18. 爆炸下限（%,V\u002FV）：未确定\n19. 溶解性：溶于丙酮，略溶于乙醇或氯仿，几乎不溶于水。溶于稀氢氧化钠溶液，在稀酸中几乎不溶。无臭，味微苦。",{"pictogram":255,"signal":256,"hazards":257},"Irritant","Warning",[258],"H302 — Harmful if swallowed \u002F 吞咽有害",[],[261,264,267,270,273,276,279,282],{"key":262,"value":263},"描述","Probenecid 是一种有效的选择性瞬时受体电位香草酸受体通道 2 (TRPV2) 激动剂。",{"key":265,"value":266},"相关类别","信号通路\n>>\n跨膜转运\n>>\nTRP频道\n研究领域\n>>\n代谢疾病",{"key":268,"value":269},"靶点","TRPV2[1]",{"key":271,"value":272},"体外研究","Probenecid有效抑制MRP1和MRP2对ATP依赖性活性囊泡N-乙基马来酰亚胺谷胱甘肽(NEM-GS)的摄取。在较高的有机阴离子浓度下观察到MRP1-ATP酶的显着抑制。相反,MRP2的ATP酶活性受到Probenecid(近似KACT =250μM),磺吡酮(KACT =300μM)和吲哚美辛(KACT =150μM)的强烈刺激,并且ATP酶活化甚至强于NEM-GS。 MRP2-ATP酶的有机阴离子活化遵循钟形曲线,对于Probenecid,最大值为约2mM,对于磺吡酮为800μM,对于吲哚美辛为400μM[2]。 Probenecid是hTAS2R16,hTAS2R38和hTAS2R43苦味受体的抑制剂。 Probenecid作用于TAS2R的一个子集,并通过一种新颖的变构作用机制进行抑制。 Probenecid还常用于增强GPCR钙动员测定中的细胞信号。 Probenecid特异性地抑制由苦味受体hTAS2R16介导的细胞反应,并提供使用非竞争性(变构)机制与该GPCR直接相互作用的分子和药理学证据[3]。",{"key":274,"value":275},"体内研究","在给予盐水的对照小鼠中,对WT小鼠施用丙磺舒导致收缩性增加,如通过相对于EF的射血分数(EF)测量的。注射后5分钟内注意到收缩力增加,所有剂量均为75 mg\u002Fkg或以上(峰值变化为5.26±3.35,8.40±2.80,7.32±2.52为75mg\u002Fkg,100mg\u002Fkg和200mg\u002Fkg,分别)。以5分钟间隔(总共30分钟)测量的测量的收缩性变化显示出收缩性的剂量依赖性增加,估计的EC50为49.33mg\u002Fkg。 EF对受试者(n = 5,剂量为200 mg\u002Fkg IV)保持升高状态至少1小时,评估时间较长(EF相对于基线平均增加8.9±2.57)[1] ]。",{"key":277,"value":278},"细胞实验","使用Lipofectamine 2000在具有透明底部的聚赖氨酸包被的黑色384孔板中用hTAS2R表达构建体转染HEK-293T细胞，并在37℃温育22小时。除去生长培养基，用含有20mM HEPES的HBSS洗涤细胞两次，然后在含有20mM HEPES（钙4测定试剂盒）的HBSS中加载钙指示剂染料，含有或不含1mM丙磺舒。在染料和丙磺舒的存在下，将细胞在37℃下孵育1小时，然后移至设定为32℃的Flexstation II-384。在15分钟的温度平衡（没有洗出）后，注射指定的化合物（在t = ~25秒）并测量荧光100至180秒，每3秒读取一次。使用Prism 5.0软件分析数据集并表示为基线信号的％。对于Schild图，原始钙通量值的重复表示为相对于基线信号的％。将指定浓度的Probenecid存在下每种浓度的TAS2R配体在36秒（对应于最大通量信号）的平均值相对于配体浓度的对数作图。使用GraphPad Prism [1]中的非线性回归拟合数据点。",{"key":280,"value":281},"动物实验","小鼠[1]为了获得剂量反应曲线，用异氟烷麻醉12-16周龄的雄性C57 WT（n = 39）小鼠，同时在显微镜下获得静脉内颈静脉通路（IV）。随后，如下所述，在胸骨旁长轴（PSLAX）中获得具有M模式和B模式的超声心动图研究。对于WT小鼠中的初始收缩性研究，注射生理盐水或不同剂量的丙磺舒（增加2至200mg \u002F kg）（推注IV）。",{"key":283,"value":284},"参考文献","[1].\nKoch SE, et al. Probenecid: novel use as a non-injurious positive inotrope acting via cardiac TRPV2 stimulation. J Mol Cell Cardiol. 2012 Jul;53(1):134-44.\n[2].\nBakos E, et al. Interactions of the human multidrug resistance proteins MRP1 and MRP2 with organic anions. Mol Pharmacol. 2000 Apr;57(4):760-8.\n[3].\nGreene TA, et al. Probenecid inhibits the human bitter taste receptor TAS2R16 and suppresses bitter perception of salicin. PLoS One. 2011;6(5):e20123.",[286,292,298,304,310],{"slug":287,"cid":288,"name":289,"nameZh":289,"cas":290,"imgSvg":291},"785896529146679300","J-44383-4","4-氯磺酰基苯甲酸","10130-89-9","https:\u002F\u002Fapi.chemical.xiaokangmed.com\u002Fimages\u002Fchem_structures_svg\u002F027\u002F10130-89-9.svg",{"slug":293,"cid":294,"name":295,"nameZh":295,"cas":296,"imgSvg":297},"785881384068583400","J-1065071-2","二正丙胺","142-84-7","https:\u002F\u002Fapi.chemical.xiaokangmed.com\u002Fimages\u002Fchem_structures_svg\u002F364\u002F142-84-7.svg",{"slug":299,"cid":300,"name":301,"nameZh":301,"cas":302,"imgSvg":303},"785894643416961000","J-38437-2","对甲苯磺酰胺","70-55-3","https:\u002F\u002Fapi.chemical.xiaokangmed.com\u002Fimages\u002Fchem_structures_svg\u002F398\u002F70-55-3.svg",{"slug":305,"cid":306,"name":307,"nameZh":307,"cas":308,"imgSvg":309},"785881670875091000","J-20582-3","卡西尼特","138-41-0","https:\u002F\u002Fapi.chemical.xiaokangmed.com\u002Fimages\u002Fchem_structures_svg\u002F035\u002F138-41-0.svg",{"slug":311,"cid":312,"name":313,"nameZh":313,"cas":314,"imgSvg":315},"785882393889214500","J-3532-5","溴代丙烷","106-94-5","https:\u002F\u002Fapi.chemical.xiaokangmed.com\u002Fimages\u002Fchem_structures_svg\u002F329\u002F106-94-5.svg",[317],{"slug":318,"cid":319,"name":320,"nameZh":320,"cas":321,"imgSvg":322},"785875450734841900","J-9851-1","4-二丙氨磺酰苄氧基氯","29171-72-0","https:\u002F\u002Fapi.chemical.xiaokangmed.com\u002Fimages\u002Fchem_structures_svg\u002F091\u002F29171-72-0.svg",[324,327,330,333],{"key":325,"value":326},"海关编码","2935009090",{"key":328,"value":329},"中文概述","2935009090 其他磺（酰）胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:35.0%",{"key":331,"value":332},"申报要素","品名, 成分含量, 用途",{"key":334,"value":335},"Summary","2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%",[337,340,342,345,348,351,354,357,360,363,366,369],{"key":338,"value":339},"符号","GHS07",{"key":341,"value":256},"信号词",{"key":343,"value":344},"危害声明","H302",{"key":346,"value":347},"警示性声明","P301 + P312 + P330",{"key":349,"value":350},"个人防护装备","dust mask type N95 (US);Eyeshields;Gloves",{"key":352,"value":353},"危害码 (欧洲)","Xn:Harmful",{"key":355,"value":356},"风险声明 (欧洲)","R22;R40",{"key":358,"value":359},"安全声明 (欧洲)","S36\u002F37",{"key":361,"value":362},"危险品运输编码","3249",{"key":364,"value":365},"WGK德国","3",{"key":367,"value":368},"RTECS号","DG9400000",{"key":325,"value":326},"\u003Ctd>\n\n\u003Cp>\u003Ca href=\"\u002Fen\u002Fcas\u002F57-66-9_242920.html#duXinDiv\">丙磺舒毒性英文版\u003C\u002Fa>\u003C\u002Fp>\n\n\u003C\u002Ftd>","\u003Cp> 对甲苯磺酰胺经重铬酸钠氧化为对羧苯磺酰胺，再用溴丙烷进行烷基化反应，所得丙磺舒钠用乙酸酸化即得丙磺舒。\u003Cbr \u002F>\u003Cbr \u002F> \u003C\u002Fp>","\u003Ctd>\n\n\u003Cb>1.1 产品标识符\u003C\u002Fb>\n\u003Cbr \u002F> : Probenecid\n\u003Cbr \u002F> 产品名称\n\u003Cbr \u002F>\n\u003Cb>1.2 鉴别的其他方法\u003C\u002Fb>\n\u003Cbr \u002F> p-(Dipropylsulfamoyl)benzoic acid\n\u003Cbr \u002F>\n\u003Cb>1.3 有关的确定了的物质或混合物的用途和建议不适合的用途\u003C\u002Fb>\n\u003Cbr \u002F> 仅供科研用途，不作为药物、家庭备用药或其它用途。\n\u003Cbr \u002F>\n\n\u003Cstrong>模块2. 危险性概述\u003C\u002Fstrong>\n\u003Cbr \u002F>\n\u003Cb>2.1 GHS分类\u003C\u002Fb>\n\u003Cbr \u002F> 急性毒性, 经口 (类别4)\n\u003Cbr \u002F>\n\u003Cb>2.2 GHS 标记要素，包括预防性的陈述\u003C\u002Fb>\n\u003Cbr \u002F> 象形图\n\u003Cbr \u002F> 警示词警告\n\u003Cbr \u002F> 危险申明\n\u003Cbr \u002F> H302吞咽有害。\n\u003Cbr \u002F> 警告申明\n\u003Cbr \u002F> 预防\n\u003Cbr \u002F> P264操作后彻底清洁皮肤。\n\u003Cbr \u002F> P270使用本产品时不要进食、饮水或吸烟。\n\u003Cbr \u002F> 措施\n\u003Cbr \u002F> P301 + P312如果吞下去了: 如感觉不适，呼救解毒中心或看医生。\n\u003Cbr \u002F> P330漱口。\n\u003Cbr \u002F> 处理\n\u003Cbr \u002F> P501将内容物\u002F 容器处理到得到批准的废物处理厂。\n\u003Cbr \u002F>\n\u003Cb>2.3 其它危害物 - 无\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块3. 成分\u002F组成信息\u003C\u002Fstrong>\n\u003Cbr \u002F>\n\u003Cb>3.1 物 质\u003C\u002Fb>\n\u003Cbr \u002F> : p-(Dipropylsulfamoyl)benzoic acid\n\u003Cbr \u002F> 别名\n\u003Cbr \u002F> : C13H19NO4S\n\u003Cbr \u002F> 分子式\n\u003Cbr \u002F> : 285.36 g\u002Fmol\n\u003Cbr \u002F> 分子量\n\u003Cbr \u002F> 组分浓度或浓度范围\n\u003Cbr \u002F> Probenecid\n\u003Cbr \u002F> -\n\u003Cbr \u002F> CAS 号57-66-9\n\u003Cbr \u002F> EC-编号200-344-3\n\u003Cbr \u002F>\n\n\u003Cstrong>模块4. 急救措施\u003C\u002Fstrong>\n\u003Cbr \u002F>\n\u003Cb>4.1 必要的急救措施描述\u003C\u002Fb>\n\u003Cbr \u002F> 一般的建议\n\u003Cbr \u002F> 请教医生。 出示此安全技术说明书给到现场的医生看。\n\u003Cbr \u002F> 吸入\n\u003Cbr \u002F> 如果吸入,请将患者移到新鲜空气处。 如果停止了呼吸,给于人工呼吸。 请教医生。\n\u003Cbr \u002F> 皮肤接触\n\u003Cbr \u002F> 用肥皂和大量的水冲洗。 请教医生。\n\u003Cbr \u002F> 眼睛接触\n\u003Cbr \u002F> 用水冲洗眼睛作为预防措施。\n\u003Cbr \u002F> 食入\n\u003Cbr \u002F> 切勿给失去知觉者从嘴里喂食任何东西。 用水漱口。 请教医生。\n\u003Cbr \u002F>\n\u003Cb>4.2 主要症状和影响，急性和迟发效应\u003C\u002Fb>\n\u003Cbr \u002F> 消化系统失调, 恶心, 头晕, 头痛, 皮炎, 尿频\n\u003Cbr \u002F>\n\u003Cb>4.3 及时的医疗处理和所需的特殊处理的说明和指示\u003C\u002Fb>\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F>\n\n\u003Cstrong>模块5. 消防措施\u003C\u002Fstrong>\n\u003Cbr \u002F>\n\u003Cb>5.1 灭火介质\u003C\u002Fb>\n\u003Cbr \u002F> 灭火方法及灭火剂\n\u003Cbr \u002F> 用水雾,耐醇泡沫,干粉或二氧化碳灭火。\n\u003Cbr \u002F>\n\u003Cb>5.2 源于此物质或混合物的特别的危害\u003C\u002Fb>\n\u003Cbr \u002F> 碳氧化物, 氮氧化物, 硫氧化物\n\u003Cbr \u002F>\n\u003Cb>5.3 给消防员的建议\u003C\u002Fb>\n\u003Cbr \u002F> 如必要的话,戴自给式呼吸器去救火。\n\u003Cbr \u002F>\n\u003Cb>5.4 进一步信息\u003C\u002Fb>\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F>\n\n\u003Cstrong>模块6. 泄露应急处理\u003C\u002Fstrong>\n\u003Cbr \u002F>\n\u003Cb>6.1 人员的预防,防护设备和紧急处理程序\u003C\u002Fb>\n\u003Cbr \u002F> 使用个人防护设备。 防止粉尘的生成。 防止吸入蒸汽、气雾或气体。 保证充分的通风。 避免吸入粉尘。\n\u003Cbr \u002F>\n\u003Cb>6.2 环境保护措施\u003C\u002Fb>\n\u003Cbr \u002F> 不要让产物进入下水道。\n\u003Cbr \u002F>\n\u003Cb>6.3 抑制和清除溢出物的方法和材料\u003C\u002Fb>\n\u003Cbr \u002F> 收集、处理泄漏物，不要产生灰尘。 扫掉和铲掉。 存放进适当的闭口容器中待处理。\n\u003Cbr \u002F>\n\u003Cb>6.4 参考其他部分\u003C\u002Fb>\n\u003Cbr \u002F> 丢弃处理请参阅第13节。\n\u003Cbr \u002F>\n\n\u003Cstrong>模块7. 操作处置与储存\u003C\u002Fstrong>\n\u003Cbr \u002F>\n\u003Cb>7.1 安全操作的注意事项\u003C\u002Fb>\n\u003Cbr \u002F> 避免接触皮肤和眼睛。 防止粉尘和气溶胶生成。\n\u003Cbr \u002F> 在有粉尘生成的地方,提供合适的排风设备。一般性的防火保护措施。\n\u003Cbr \u002F>\n\u003Cb>7.2 安全储存的条件,包括任何不兼容性\u003C\u002Fb>\n\u003Cbr \u002F> 贮存在阴凉处。 容器保持紧闭，储存在干燥通风处。\n\u003Cbr \u002F>\n\u003Cb>7.3 特定用途\u003C\u002Fb>\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F>\n\n\u003Cstrong>模块8. 接触控制和个体防护\u003C\u002Fstrong>\n\u003Cbr \u002F>\n\u003Cb>8.1 容许浓度\u003C\u002Fb>\n\u003Cbr \u002F> 最高容许浓度\n\u003Cbr \u002F> 没有已知的国家规定的暴露极限。\n\u003Cbr \u002F>\n\u003Cb>8.2 暴露控制\u003C\u002Fb>\n\u003Cbr \u002F> 适当的技术控制\n\u003Cbr \u002F> 按照良好工业和安全规范操作。 休息前和工作结束时洗手。\n\u003Cbr \u002F> 个体防护设备\n\u003Cbr \u002F> 眼\u002F面保护\n\u003Cbr \u002F> 带有防护边罩的安全眼镜符合 EN166要求请使用经官方标准如NIOSH (美国) 或 EN 166(欧盟)\n\u003Cbr \u002F> 检测与批准的设备防护眼部。\n\u003Cbr \u002F> 皮肤保护\n\u003Cbr \u002F> 戴手套取 手套在使用前必须受检查。\n\u003Cbr \u002F> 请使用合适的方法脱除手套(不要接触手套外部表面),避免任何皮肤部位接触此产品.\n\u003Cbr \u002F> 使用后请将被污染过的手套根据相关法律法规和有效的实验室规章程序谨慎处理. 请清洗并吹干双手\n\u003Cbr \u002F> 所选择的保护手套必须符合EU的89\u002F686\u002FEEC规定和从它衍生出来的EN 376标准。\n\u003Cbr \u002F> 身体保护\n\u003Cbr \u002F> 全套防化学试剂工作服, 防护设备的类型必须根据特定工作场所中的危险物的浓度和含量来选择。\n\u003Cbr \u002F> 呼吸系统防护\n\u003Cbr \u002F> 如须暴露于有害环境中,请使用P95型(美国)或P1型(欧盟 英国\n\u003Cbr \u002F> 143)防微粒呼吸器。如需更高级别防护,请使用OV\u002FAG\u002FP99型(美国)或ABEK-P2型 (欧盟 英国 143)\n\u003Cbr \u002F> 防毒罐。\n\u003Cbr \u002F> 呼吸器使用经过测试并通过政府标准如NIOSH（US）或CEN（EU）的呼吸器和零件。\n\u003Cbr \u002F>\n\n\u003Cstrong>模块9. 理化特性\u003C\u002Fstrong>\n\u003Cbr \u002F>\n\u003Cb>9.1 基本的理化特性的信息\u003C\u002Fb>\n\u003Cbr \u002F> a) 外观与性状\n\u003Cbr \u002F> 形状: 固体\n\u003Cbr \u002F> b) 气味\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F> c) 气味阈值\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F> d) pH值\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F> e) 熔点\u002F凝固点\n\u003Cbr \u002F> 熔点\u002F凝固点: 198 - 200 °C\n\u003Cbr \u002F> f) 起始沸点和沸程\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F> g) 闪点\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F> h) 蒸发速率\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F> i) 易燃性(固体,气体)\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F> j) 高的\u002F低的燃烧性或爆炸性限度 无数据资料\n\u003Cbr \u002F> k) 蒸汽压\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F> l) 蒸汽密度\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F> m) 相对密度\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F> n) 水溶性\n\u003Cbr \u002F> 不溶, 部分溶解\n\u003Cbr \u002F> o) n-辛醇\u002F水分配系数\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F> p) 自燃温度\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F> q) 分解温度\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F> r) 粘度\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F>\n\n\u003Cstrong>模块10. 稳定性和反应活性\u003C\u002Fstrong>\n\u003Cbr \u002F>\n\u003Cb>10.1 反应性\u003C\u002Fb>\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F>\n\u003Cb>10.2 稳定性\u003C\u002Fb>\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F>\n\u003Cb>10.3 危险反应的可能性\u003C\u002Fb>\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F>\n\u003Cb>10.4 应避免的条件\u003C\u002Fb>\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F>\n\u003Cb>10.5 不兼容的材料\u003C\u002Fb>\n\u003Cbr \u002F> 强氧化剂\n\u003Cbr \u002F>\n\u003Cb>10.6 危险的分解产物\u003C\u002Fb>\n\u003Cbr \u002F> 其它分解产物 - 无数据资料\n\u003Cbr \u002F>\n\n\u003Cstrong>模块11. 毒理学资料\u003C\u002Fstrong>\n\u003Cbr \u002F>\n\u003Cb>11.1 毒理学影响的信息\u003C\u002Fb>\n\u003Cbr \u002F> 急性毒性\n\u003Cbr \u002F> 半数致死剂量 (LD50) 经口 - 大鼠 - 1,600 mg\u002Fkg\n\u003Cbr \u002F> 皮肤刺激或腐蚀\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F> 眼睛刺激或腐蚀\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F> 呼吸道或皮肤过敏\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F> 生殖细胞突变性\n\u003Cbr \u002F> 细胞突变性-体外试验 - 仓鼠 - 子宫\n\u003Cbr \u002F> 姐妹染色单体互换\n\u003Cbr \u002F> 致癌性\n\u003Cbr \u002F> 致癌性 - 老鼠 - 经口\n\u003Cbr \u002F> 肿瘤发生：符合RTECS标准的成瘤性。 肝脏：肿瘤\n\u003Cbr \u002F> 该产品不是或不包含被IARC, ACGIH, EPA, 和 NTP 列为致癌物的组分\n\u003Cbr \u002F> IARC:\n\u003Cbr \u002F> 此产品中没有大于或等于 0。1%含量的组分被 IARC鉴别为可能的或肯定的人类致癌物。\n\u003Cbr \u002F> 生殖毒性\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F> 特异性靶器官系统毒性（一次接触）\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F> 特异性靶器官系统毒性（反复接触）\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F> 吸入危险\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F> 潜在的健康影响\n\u003Cbr \u002F> 吸入吸入可能有害。 可能引起呼吸道刺激。\n\u003Cbr \u002F> 摄入误吞对人体有害。\n\u003Cbr \u002F> 皮肤如果通过皮肤吸收可能是有害的。 可能引起皮肤刺激。\n\u003Cbr \u002F> 眼睛可能引起眼睛刺激。\n\u003Cbr \u002F> 接触后的征兆和症状\n\u003Cbr \u002F> 消化系统失调, 恶心, 头晕, 头痛, 皮炎, 尿频\n\u003Cbr \u002F> 附加说明\n\u003Cbr \u002F> 化学物质毒性作用登记: DG9400000\n\u003Cbr \u002F>\n\n\u003Cstrong>模块12. 生态学资料\u003C\u002Fstrong>\n\u003Cbr \u002F>\n\u003Cb>12.1 生态毒性\u003C\u002Fb>\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F>\n\u003Cb>12.2 持久存留性和降解性\u003C\u002Fb>\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F>\n\u003Cb>12.3 潜在的生物蓄积性\u003C\u002Fb>\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F>\n\u003Cb>12.4 土壤中的迁移性\u003C\u002Fb>\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F>\n\u003Cb>12.5 PBT 和 vPvB的结果评价\u003C\u002Fb>\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F>\n\u003Cb>12.6 其它不利的影响\u003C\u002Fb>\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F>\n\n\u003Cstrong>模块13. 废弃处置\u003C\u002Fstrong>\n\u003Cbr \u002F>\n\u003Cb>13.1 废物处理方法\u003C\u002Fb>\n\u003Cbr \u002F> 产品\n\u003Cbr \u002F> 将剩余的和未回收的溶液交给处理公司。 联系专业的拥有废弃物处理执照的机构来处理此物质。\n\u003Cbr \u002F> 与易燃溶剂相溶或者相混合，在备有燃烧后处理和洗刷作用的化学焚化炉中燃烧\n\u003Cbr \u002F> 受污染的容器和包装\n\u003Cbr \u002F> 作为未用过的产品弃置。\n\u003Cbr \u002F>\n\n\u003Cstrong>模块14. 运输信息\u003C\u002Fstrong>\n\u003Cbr \u002F>\n\u003Cb>14.1 联合国危险货物编号\u003C\u002Fb>\n\u003Cbr \u002F> 欧洲陆运危规: -国际海运危规: -国际空运危规: -\n\u003Cbr \u002F>\n\u003Cb>14.2 联合国（UN）规定的名称\u003C\u002Fb>\n\u003Cbr \u002F> 欧洲陆运危规: 非危险货物\n\u003Cbr \u002F> 国际海运危规: 非危险货物\n\u003Cbr \u002F> 国际空运危规: 非危险货物\n\u003Cbr \u002F>\n\u003Cb>14.3 运输危险类别\u003C\u002Fb>\n\u003Cbr \u002F> 欧洲陆运危规: -国际海运危规: -国际空运危规: -\n\u003Cbr \u002F>\n\u003Cb>14.4 包裹组\u003C\u002Fb>\n\u003Cbr \u002F> 欧洲陆运危规: -国际海运危规: -国际空运危规: -\n\u003Cbr \u002F>\n\u003Cb>14.5 环境危险\u003C\u002Fb>\n\u003Cbr \u002F> 欧洲陆运危规: 否国际海运危规 海运污染物: 否国际空运危规: 否\n\u003Cbr \u002F>\n\u003Cb>14.6 对使用者的特别提醒\u003C\u002Fb>\n\u003Cbr \u002F> 无数据资料\n\u003Cbr \u002F>\n\u003Cbr \u002F>\n\n\u003Cstrong> 模块 15 - 法规信息 \u003C\u002Fstrong>\n\u003Cbr \u002F>N\u002FA\n\u003Cbr \u002F>\n\u003Cbr \u002F>\n\n\u003Cstrong> 模块16 - 其他信息 \u003C\u002Fstrong>\n\u003Cbr \u002F>N\u002FA\n\u003Cbr \u002F>\u003Cbr \u002F>\u003Cbr \u002F>\u003Cbr \u002F>\u003Cbr \u002F>\n\u003Cbr \u002F>\n\u003C\u002Ftd>","2026-08-21T07:51:12.859463Z",false,[376,382,388,394,400,406,412,418,424,429,435,441],{"slug":377,"cid":378,"name":379,"nameZh":380,"cas":381},"785894562861158400","J-38022-3","Luteolin","木犀草素","491-70-3",{"slug":383,"cid":384,"name":385,"nameZh":386,"cas":387},"785889602677248000","J-1959100-5","Ataluren","阿塔鲁伦","775304-57-9",{"slug":389,"cid":390,"name":391,"nameZh":392,"cas":393},"785884649673986048","J-23784-3","Ammonium ferrocyanide","亚铁氰化铵","14481-29-9",{"slug":395,"cid":396,"name":397,"nameZh":398,"cas":399},"785872087020474368","J-1990991-2","Alizarin Yellow R","茜素黄R","2243-76-7",{"slug":401,"cid":402,"name":403,"nameZh":404,"cas":405},"785883053602902016","J-6816-6","Neutral Red","中性红","553-24-2",{"slug":407,"cid":408,"name":409,"nameZh":410,"cas":411},"785883839846158336","J-9665-1","propineb","丙森锌","12071-83-9",{"slug":413,"cid":414,"name":415,"nameZh":416,"cas":417},"785882572998578176","J-1361907-3","Methyl Red sodium salt","甲基红钠盐","845-10-3",{"slug":419,"cid":420,"name":421,"nameZh":422,"cas":423},"785897942564212736","J-1098773-2","Giemsa stain","吉氏色素","51811-82-6",{"slug":425,"cid":426,"name":427,"nameZh":427,"cas":428},"785900657373614080","J-1622860-7","8-Chloro-1-phenyldibenzofuran","809274-52-0",{"slug":430,"cid":431,"name":432,"nameZh":433,"cas":434},"785883770937937920","J-1394584-1","Calcium ferrocyanide","亚铁氰化钙","13821-08-4",{"slug":436,"cid":437,"name":438,"nameZh":439,"cas":440},"785898686344335360","J-1174132-5","Pigment Red 83","颜料红 83","104074-25-1",{"slug":442,"cid":443,"name":444,"nameZh":445,"cas":446},"785882735708213248","J-5581-2","METHYL CALCEIN BLUE","甲基钙黄绿素","54696-41-2",1794254223121,"zh-CN",[]]