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100g食物的硫胺素浓度（盐酸硫胺素，MW = 337.3）。根据“实验室啮齿动物的纯化日粮”制备两种硫胺素限制食品，其中硫胺素浓度为0.60 mg \u002F 100 g食品（35％常规食品硫胺素）或0.27 mg \u002F 100 g食品（16％硫胺素）传统食品）。含有高硫胺素的食物也是由AIN-93M制备的，其中硫胺素浓度是CE-2的5倍（硫胺素：8.50mg \u002F 100g食物）[2]。",{"key":240,"value":241},"参考文献","[1].\nKenneth Osiezagha, et al.Thiamine Deficiency and Delirium. 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tariff:20.0%",[270,273,276,279,282],{"key":271,"value":272},"危害码 (欧洲)","Xn",{"key":274,"value":275},"安全声明 (欧洲)","S22-S24\u002F25",{"key":277,"value":278},"危险品运输编码","NONH for all modes of transport",{"key":280,"value":281},"RTECS号","XI7400000",{"key":258,"value":259},"\u003Ctd>\n\n\u003Cp>\u003Cstrong>硝酸硫胺毒理学数据:\u003C\u002Fstrong>\u003C\u002Fp>\n\u003Cp>\u003C\u002Fp>\u003Cp>急性毒性：兔子经静脉LD50：113mg\u002Fkg，行为-肌肉收缩或痉挛，紫绀肺，胸部或呼吸-其他变化；  \u003C\u002Fp>\n\u003Cp>小鼠经口LD50：>   5gm \u002Fkg，除致死剂量外无详细说明； \u003C\u002Fp>\n\u003Cp>小鼠经腹腔LD50：387mg\u002Fkg，行为-肌肉收缩或痉挛，紫绀肺，胸部或呼吸-其他变化； \u003C\u002Fp>\n\u003Cp>小鼠经静脉LD50：84mg\u002Fkg，行为-肌肉收缩或痉挛，紫绀肺，胸部或呼吸-其他变化； \u003C\u002Fp>\n\u003Cp>狗经静脉LD50：350mg\u002Fkg，除致死剂量外无详细说明； \u003C\u002Fp>\n\u003Cp>兔子经静脉LD50：300mg\u002Fkg，除致死剂量外无详细说明； \u003C\u002Fp>\n\u003Cp>\u003C\u002Fp>\n\u003Cp>\u003Cstrong>硝酸硫胺生态学数据:\u003C\u002Fstrong>\u003C\u002Fp>\n\u003Cp>\u003C\u002Fp>\u003Cp>该物质对环境可能有危害，对水体应给予特别注意。  \u003C\u002Fp>\n\u003Cp>\u003C\u002Fp>\n\u003Cp>\u003Ca href=\"\u002Fen\u002Fcas\u002F532-43-4_951935.html#duXinDiv\">硝酸硫胺毒性英文版\u003C\u002Fa>\u003C\u002Fp>\n\n\u003C\u002Ftd>","\u003Cp> 维生素B1自然存在于米糠、麸皮、瘦肉、花生米等食物中，纯品通常由化学合成制备。过量的盐酸乙脒在碱性（甲醇和甲醇钠）介质中与α-二甲氧基-β-甲氧基丙腈缩合为3，6-二甲基-1，2-二氢-2，4，5，7-四氮萘，然后在98-100℃下水解，再在碱性条件下开环生成2-甲基-4-氨基-5-氨甲基嘧啶；接着与二硫化碳和氨水作用，然后与乙酸-γ-氯代-γ-乙酰丙酯缩合，再在盐酸中、75-78℃下水解和环合成硫代硫胺盐酸盐，最后用氨水中和、过氧化氢氧化、盐酸酸化得硫胺盐酸盐。 \u003C\u002Fp>","\u003Ctd>\n\r\n                                        \r\n                                        硝酸硫胺\n\u003Cb>修改号码：5\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块1. 化学品\u003C\u002Fstrong>\n\u003Cbr \u002F> 产品名称：\n\u003Cb>Thiamine Nitrate\u003C\u002Fb>\n\u003Cbr \u002F> 修改号码：\n\u003Cb>5\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块2. 危险性概述\u003C\u002Fstrong>\n\u003Cbr \u002F>\n\u003Cb>GHS分类\u003C\u002Fb>\n\u003Cbr \u002F> 　物理性危害未分类\n\u003Cbr \u002F> 　健康危害未分类\n\u003Cbr \u002F> 　环境危害未分类\n\u003Cbr \u002F>\n\u003Cb>GHS标签元素\u003C\u002Fb>\n\u003Cbr \u002F> 　图标或危害标志无\n\u003Cbr \u002F> 　信号词无信号词\n\u003Cbr \u002F> 　危险描述无\n\u003Cbr \u002F> 　防范说明无\n\u003Cbr \u002F>\n\n\u003Cstrong>模块3. 成分\u002F组成信息\u003C\u002Fstrong>\n\u003Cbr \u002F>\n\u003Cb>单一物质\u002F混和物\u003C\u002Fb>单一物质\n\u003Cbr \u002F>\n\u003Cb>化学名(中文名)：\u003C\u002Fb>硝酸硫胺\n\u003Cbr \u002F> 百分比：\n\u003Cb>>98.0%(LC)(E)\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>CAS编码：\u003C\u002Fb>\n\u003Cb>532-43-4\u003C\u002Fb>\n\u003Cbr \u002F> 俗名：\n\u003Cb>Vitamin B1 Nitrate\u003C\u002Fb>\n\u003Cbr \u002F> 分子式：\n\u003Cb>C12H17N5O4S\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块4. 急救措施\u003C\u002Fstrong>\n\u003Cbr \u002F> 吸入：\n\u003Cb>将受害者移到新鲜空气处，保持呼吸通畅，休息。若感不适请求医\u002F就诊。\u003C\u002Fb>\n\u003Cbr \u002F> 皮肤接触：\n\u003Cb>立即去除\u002F脱掉所有被污染的衣物。用水清洗皮肤\u002F淋浴。\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>若皮肤刺激或发生皮疹：求医\u002F就诊。\u003C\u002Fb>\n\u003Cbr \u002F> 眼睛接触：用水小心清洗几分钟。如果方便，易操作，摘除隐形眼镜。继续清洗。\n\u003Cbr \u002F>\n\u003Cb>如果眼睛刺激：求医\u002F就诊。\u003C\u002Fb>\n\u003Cbr \u002F> 食入：\n\u003Cb>若感不适，求医\u002F就诊。漱口。\u003C\u002Fb>\n\u003Cbr \u002F> 紧急救助者的防护：救援者需要穿戴个人防护用品，比如橡胶手套和气密性护目镜。\n\u003Cbr \u002F>\n\n\u003Cstrong>模块5. 消防措施\u003C\u002Fstrong>\n\u003Cbr \u002F> 合适的灭火剂：干粉，泡沫，雾状水，二氧化碳\n\u003Cbr \u002F> 特殊危险性：小心，燃烧或高温下可能分解产生毒烟。\n\u003Cbr \u002F> 硝酸硫胺\n\u003Cb>修改号码：5\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块5. 消防措施\u003C\u002Fstrong>\n\u003Cbr \u002F> 特定方法：从上风处灭火，根据周围环境选择合适的灭火方法。\n\u003Cbr \u002F> 非相关人员应该撤离至安全地方。\n\u003Cbr \u002F> 周围一旦着火：如果安全，移去可移动容器。\n\u003Cbr \u002F> 消防员的特殊防护用具：灭火时，一定要穿戴个人防护用品。\n\u003Cbr \u002F>\n\n\u003Cstrong>模块6. 泄漏应急处理\u003C\u002Fstrong>\n\u003Cbr \u002F> 个人防护措施，防护用具，\n\u003Cb>使用个人防护用品。远离溢出物\u002F泄露处并处在上风处。\u003C\u002Fb>\n\u003Cbr \u002F> 紧急措施：泄露区应该用安全带等圈起来，控制非相关人员进入。\n\u003Cbr \u002F> 环保措施：防止进入下水道。\n\u003Cbr \u002F> 控制和清洗的方法和材料：清扫收集粉尘，封入密闭容器。注意切勿分散。附着物或收集物应该立即根据合适的\n\u003Cbr \u002F> 法律法规处置。\n\u003Cbr \u002F>\n\n\u003Cstrong>模块7. 操作处置与储存\u003C\u002Fstrong>\n\u003Cbr \u002F> 处理\n\u003Cbr \u002F> 技术措施：在通风良好处进行处理。穿戴合适的防护用具。防止粉尘扩散。处理后彻底清洗双手\n\u003Cbr \u002F> 和脸。\n\u003Cbr \u002F> 注意事项：如果粉尘或浮质产生，使用局部排气。\n\u003Cbr \u002F> 操作处置注意事项：避免接触皮肤、眼睛和衣物。\n\u003Cbr \u002F> 贮存\n\u003Cbr \u002F> 储存条件：保持容器密闭。存放于凉爽、阴暗处。\n\u003Cbr \u002F> 远离不相容的材料比如氧化剂存放。\n\u003Cbr \u002F> 包装材料：依据法律。\n\u003Cbr \u002F>\n\n\u003Cstrong>模块8. 接触控制和个体防护\u003C\u002Fstrong>\n\u003Cbr \u002F> 工程控制：尽可能安装封闭体系或局部排风系统，操作人员切勿直接接触。同时安装淋浴器和洗\n\u003Cbr \u002F> 眼器。\n\u003Cbr \u002F> 个人防护用品\n\u003Cbr \u002F> 　呼吸系统防护：防尘面具。依据当地和政府法规。\n\u003Cbr \u002F> 　手部防护：防护手套。\n\u003Cbr \u002F> 　眼睛防护：安全防护镜。如果情况需要，佩戴面具。\n\u003Cbr \u002F> 　皮肤和身体防护：防护服。如果情况需要，穿戴防护靴。\n\u003Cbr \u002F>\n\n\u003Cstrong>模块9. 理化特性\u003C\u002Fstrong>\n\u003Cbr \u002F> 固体\n\u003Cbr \u002F>\n\u003Cb>外形（20°C）：\u003C\u002Fb>\n\u003Cbr \u002F> 外观：\n\u003Cb>晶体-粉末\u003C\u002Fb>\n\u003Cbr \u002F> 颜色：\n\u003Cb>白色-微浅黄色\u003C\u002Fb>\n\u003Cbr \u002F> 气味：几乎无味\n\u003Cbr \u002F>\n\u003Cb>pH:\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>6.5 - 8.0 (10g\u002FL H2O 20°C)\u003C\u002Fb>\n\u003Cbr \u002F> 熔点：\n\u003Cb>190°C\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>沸点\u002F沸程\u003C\u002Fb>无资料\n\u003Cbr \u002F> 闪点：无资料\n\u003Cbr \u002F> 爆炸特性\n\u003Cbr \u002F> 　爆炸下限：无资料\n\u003Cbr \u002F> 　爆炸上限：无资料\n\u003Cbr \u002F> 密度：无资料\n\u003Cbr \u002F> 溶解度：\n\u003Cbr \u002F>\n\u003Cb>[水]\u003C\u002Fb>\n\u003Cb>微溶于(2.7g\u002F100mL, 25°C)\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>[其他溶剂]\u003C\u002Fb>\n\u003Cbr \u002F> 微溶于：\n\u003Cb>酒精, 氯仿\u003C\u002Fb>\n\u003Cbr \u002F> 硝酸硫胺\n\u003Cb>修改号码：5\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块10. 稳定性和反应性\u003C\u002Fstrong>\n\u003Cbr \u002F> 化学稳定性：一般情况下稳定。\n\u003Cbr \u002F> 危险反应的可能性：未报道特殊反应性。\n\u003Cbr \u002F> 须避免接触的物质氧化剂\n\u003Cbr \u002F>\n\u003Cb>危险的分解产物:\u003C\u002Fb>\n\u003Cb>一氧化碳, 二氧化碳, 氮氧化物 (NOx), 硫氧化物\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块11. 毒理学信息\u003C\u002Fstrong>\n\u003Cbr \u002F> 急性毒性：\n\u003Cb>ipr-mus LD50:387 mg\u002Fkg\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>ivn-rbt LD50:113 mg\u002Fkg\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>ivn-mus LD50:84 mg\u002Fkg\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cb>orl-mus LD:>5 g\u002Fkg\u003C\u002Fb>\n\u003Cbr \u002F> 对皮肤腐蚀或刺激：无资料\n\u003Cbr \u002F> 对眼睛严重损害或刺激：无资料\n\u003Cbr \u002F> 生殖细胞变异原性：无资料\n\u003Cbr \u002F> 致癌性：\n\u003Cbr \u002F>\n\u003Cb>IARC =\u003C\u002Fb>无资料\n\u003Cbr \u002F>\n\u003Cb>NTP =\u003C\u002Fb>无资料\n\u003Cbr \u002F> 生殖毒性：无资料\n\u003Cbr \u002F>\n\u003Cb>RTECS 号码:\u003C\u002Fb>\n\u003Cb>XI7400000\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块12. 生态学信息\u003C\u002Fstrong>\n\u003Cbr \u002F> 生态毒性：\n\u003Cbr \u002F> 鱼类：无资料\n\u003Cbr \u002F> 甲壳类：无资料\n\u003Cbr \u002F> 藻类：无资料\n\u003Cbr \u002F>\n\u003Cb>残留性 \u002F 降解性：\u003C\u002Fb>无资料\n\u003Cbr \u002F>\n\u003Cb>潜在生物累积 （BCF):\u003C\u002Fb>无资料\n\u003Cbr \u002F> 土壤中移动性\n\u003Cbr \u002F>\n\u003Cb>　log水分配系数：\u003C\u002Fb>无资料\n\u003Cbr \u002F>\n\u003Cb>　土壤吸收系数 （Koc）：\u003C\u002Fb>无资料\n\u003Cbr \u002F> 　亨利定律无资料\n\u003Cbr \u002F>\n\u003Cb>constant(PaM3\u002Fmol):\u003C\u002Fb>\n\u003Cbr \u002F>\n\n\u003Cstrong>模块13. 废弃处置\u003C\u002Fstrong>\n\u003Cbr \u002F> 如果可能，回收处理。请咨询当地管理部门。建议在可燃溶剂中溶解混合，在装有后燃和洗涤装置的化学焚烧炉中\n\u003Cbr \u002F> 焚烧。废弃处置时请遵守国家、地区和当地的所有法规。\n\u003Cbr \u002F>\n\n\u003Cstrong>模块14. 运输信息\u003C\u002Fstrong>\n\u003Cbr \u002F> 联合国分类：与联合国分类标准不一致\n\u003Cbr \u002F>\n\u003Cb>UN编号：\u003C\u002Fb>未列明\n\u003Cbr \u002F>\n\n\u003Cstrong>模块15. 法规信息\u003C\u002Fstrong>\n\u003Cbr \u002F>\n\u003Cb>《危险化学品安全管理条例》（2002年1月26日国务院发布，2011年2月16日修订）: 针对危险化学品的安全使用、\u003C\u002Fb>\n\u003Cbr \u002F> 生产、储存、运输、装卸等方面均作了相应的规定。\n\u003Cbr \u002F> 硝酸硫胺\n\u003Cb>修改号码：5\u003C\u002Fb>\n\u003Cbr \u002F>\n\u003Cbr \u002F>\n\n\u003Cstrong> 模块16 - 其他信息 \u003C\u002Fstrong>\n\u003Cbr \u002F>N\u002FA\n\u003Cbr \u002F>\u003Cbr \u002F>\u003Cbr \u002F>\n\u003Cbr \u002F>\u003Cbr \u002F>\n\u003C\u002Ftd>","2026-08-21T07:51:12.859463Z",false,[289,295,301,307,313,319,325,331,337,343,349,355],{"slug":290,"cid":291,"name":292,"nameZh":293,"cas":294},"855016484450078720","J-1994354-5","ABS-752 (hydrochloride)","ABS-752 盐酸盐","2922884-90-8",{"slug":296,"cid":297,"name":298,"nameZh":299,"cas":300},"785895821093638144","J-1981263-6","Fasudil hydrochloride","盐酸法舒地尔","105628-07-7",{"slug":302,"cid":303,"name":304,"nameZh":305,"cas":306},"785905339009601536","J-172626-7","Benzyl 11-aminoundecanoate hydrochloride","11-氨基十一烷酸苄酯盐酸盐","101778-85-2",{"slug":308,"cid":309,"name":310,"nameZh":311,"cas":312},"785881811828871168","J-21152-9","Methyl perfluorohexanoate","十一氟己酸甲酯","424-18-0",{"slug":314,"cid":315,"name":316,"nameZh":317,"cas":318},"785883812713205760","J-1174874-6","Calcium valproate","丙戊酸钙","33433-82-8",{"slug":320,"cid":321,"name":322,"nameZh":323,"cas":324},"785889759493885952","J-1378692-0","Calcium 2-ethylhexanoate","2-乙基己酸钙","136-51-6",{"slug":326,"cid":327,"name":328,"nameZh":329,"cas":330},"785891472418279424","J-1306502-6","calcium caprylate","辛酸钙","6107-56-8",{"slug":332,"cid":333,"name":334,"nameZh":335,"cas":336},"785891472565080064","J-1348387-9","Calcium isooctanoate","异辛酸钙","84777-61-7",{"slug":338,"cid":339,"name":340,"nameZh":341,"cas":342},"785883944527597568","J-41268-0","Fumaric acid monoethyl ester, calcium salt","富马酸单乙基酯钙盐","62008-22-4",{"slug":344,"cid":345,"name":346,"nameZh":347,"cas":348},"785893664441241600","J-35896-3","Retinyl acetate","维生素A醋酸酯","127-47-9",{"slug":350,"cid":351,"name":352,"nameZh":353,"cas":354},"785882234950258688","J-1133720-5","Thorium(IV) carbonate oxide monohydrate","碳酸氧钍单水合物","49741-19-7",{"slug":356,"cid":357,"name":358,"nameZh":359,"cas":360},"785871921307717632","J-1990316-3","Tetraamminepalladium(II) acetate","四氨基醋酸钯","61495-96-3",1794263501681,"zh-CN",[]]